FDA于2007年首次批准该疫苗用于主动免疫,以预防被确定为天花感染高危人群的天花疾病。 猴痘(又称MPox)是一种由双链DNA mpox病毒引起的中非和西非特有的传染病,也是一种人畜共患病,即由动物传染给人类的疾病,病例通常发生在热带雨林附近,那里有携...
ACAM2000天花..开发商 Emergent BioSolutions 在新闻稿中宣布,FDA 已批准一项补充生物制品许可申请,以扩大 ACAM2000 的适应症,包括预防感染风险高的个体的 mpox 疾病。此前,该药的
ACAM2000 是一种单剂量皮肤点刺疫苗,使用浸有疫苗溶液的分叉针经皮注射。 2022 年,世卫组织宣布第一个 mpox 公共卫生紧急事件为国际关注事件,这一全球性事件导致 115 个非流行地区蔓延了 95,000 多例病例。第一个紧急情况是由 II 型 mpox 引起的,该病毒的存活率为 99.9%,而第二个也是当前的紧急情况则是...
This study demonstrates the protective efficacy of multiple vaccine platforms against mpox virus challenge, including both current clinical vaccines and vectored subunit vaccines. Editor's summary: The global outbreak of mpox virus in 2022–2023 highlighted the need to ...
“Mpox has progressed to become an uncontrolled epidemic in Africa — prompting the WHO to declare a second public health emergency of international concern — creating an enormous need to use all effective tools to extinguish it as a threat,” said Dr. Amesh A. Adalja, FIDSA FACP FACEP ...
These side effects are less likely to occur in people who have already been vaccinated with a smallpox/mpox vaccine compared to those who have never been vaccinated with this type of vaccine before. Serious side effects and warnings ACAM2000 carries aBoxed Warningfor myocarditis and pericarditis...
开发商 Emergent BioSolutions 在新闻稿中宣布,FDA 已批准一项补充生物制品许可申请,以扩大 ACAM2000 的适应症,包括预防感染风险高的个体的 mpox 疾病。 此前,该药的适应症仅限于预防天花。 此项批准得到了现有人类安全数据和动物研究的支持,这些研究证明了该疫苗对 mpox 病毒暴露的有效性。此前,Emergent 已向世...
MpoxmonkeypoxACAMvaccinesafetydoi:10.1080/14760584.2023.2198600Basant E. KatameshView further author informationMaysa MadanyView further author informationFatma LabiebView further author informationAbdelaziz Abdelaaldrabdoseliem@gmail.comView further author information...