The most important pathway interacting with FOXO in different types of cancers is the PI3K/AKT pathway. Some other important pathways such as the Ras-MEK-ERK, IKK and AMPK pathways are also associated with FOXOs in tumorigenesis. Therapeutically targeting the FOXO signaling pathway(s) could lead ...
PGC-1α Promotes Nitric Oxide Antioxidant Defenses and Inhibits FOXO Signaling Against Cardiac Cachexia in Mice 来自 学术范 喜欢 0 阅读量: 67 作者:T Geng,L Ping,X Yin,Z Yan 摘要: Chronic heart failure often results in catabolic muscle wasting, exercise intolerance, and death. Oxidative muscles...