The company plans to submit a Drug Master File to the FDA immediately, which, once approved, will allow it to distribute cGMP grade Ac-225. Before Bayer, NorthStar entered into similar agreements with Fusion Pharmaceuticals, Aktis, and Clovis. It also partnered with Convergent to use Ac-225...
nanoparticles encapsulating [225Ac]Ac3+for therapeutic applications. Encapsulation of [225Ac]Ac3+within PLGA nanoparticles was performed via active entrapment of the radionuclide during synthesis with a double-emulsion solvent evaporation method. This method was adapted to radiological applications by decreasi...
After FDA approval on 23 March 2022, treatment with177Lu-PSMA-617 is already possible for adult patients with PSMA-positive mCRPC in the USA. Although promising results have been achieved with225Ac-PSMA RNT, further developments in this field are needed before225Ac-PSMA RNT can be implemented ...
These authors found a survival gain of only 4 months between patients diagnosed in 2011–2014 versus those diagnosed in 2000–2003 and 2004–2010; docetaxel which was approved by the FDA for treatment of mCRPC in 2004, and ARSi which was approved from 2011 onwards [41]. Thus, it appears ...
Definition(定义):Orphan drug: Drugs(includes biologics)for the prevention, diagnosis, or treatment of diseases or conditions affecting fewer than 200,000 persons in the US or Drugs that will not profitable within 7 years following approval by the FDA用于预防...
今年9月,美国食品药品监督管理局(FDA)批准了全球首个口服选择性TYK2变构抑制剂(deucravacitinib)用于中重度斑块状银屑病治疗;而在同期召开的2022欧洲皮肤病与性病学会年会(EADV)上,研究者公布了该疗法首个以中国患者为主的亚洲多中心III期...
基本信息 别名- 简介- 关联 2 项与ApoE2 相关的临床试验 NCT05400330/Recruiting临床1期 Long-Term Follow-Up to Evaluate the Safety of LX1001 in Participants With APOE4 Homozygote Alzheimer's Disease The primary purpose of this long-term follow-up study is to assess the long-term safety profile...
We can't release the film until we have the approval from the authority concerned. 直到获得有关当局的批准我们才能发行那部电影。 18) so/ such(…)that(如此……以至于) With the rumor spreading fast, their anxiety was such that they could ...