nanoparticles encapsulating [225Ac]Ac3+for therapeutic applications. Encapsulation of [225Ac]Ac3+within PLGA nanoparticles was performed via active entrapment of the radionuclide during synthesis with a double-emulsion solvent evaporation method. This method was adapted to radiological applications by decreasi...
The company plans to submit a Drug Master File to the FDA immediately, which, once approved, will allow it to distribute cGMP grade Ac-225. Before Bayer, NorthStar entered into similar agreements with Fusion Pharmaceuticals, Aktis, and Clovis. It also partnered with Convergent to use Ac-225...
These authors found a survival gain of only 4 months between patients diagnosed in 2011–2014 versus those diagnosed in 2000–2003 and 2004–2010; docetaxel which was approved by the FDA for treatment of mCRPC in 2004, and ARSi which was approved from 2011 onwards [41]. Thus, it appears ...
1,* , Erik de Blois 1, Eline Hooijman 1,2, Astrid van der Veldt 1,3 and Tessa Brabander 1 1 Department of Radiology & Nuclear Medicine, Erasmus MC, 3015 GD Rotterdam, The Netherlands 2 Department of Hospital Pharmacy, Erasmus MC, 3015 GD Rotterdam, The Netherlands ...
基本信息 别名- 简介- 关联 2 项与ApoE2 相关的临床试验 NCT05400330/Recruiting临床1期 Long-Term Follow-Up to Evaluate the Safety of LX1001 in Participants With APOE4 Homozygote Alzheimer's Disease The primary purpose of this long-term follow-up study is to assess the long-term safety profile...