常用名ABT-719英文名ABT-719 CAS号162829-90-5分子量345.368 密度1.5±0.1 g/cm3沸点501.5±50.0 °C at 760 mmHg 分子式C18H20FN3O3熔点N/A MSDSN/A闪点257.1±30.1 °C Fields of Application : ABT-719 is a potent bacterial DNA gyrase inhibitor. ...
A-86719.1;A-816719.1;A 816719.1;ABT-719 HCl;ABT-719 hydrochloride;ABT719 HCl,ABT 719 HCl;ABT-719;ABT 719;ABT719;A-86719.1;4H-Quinolizine-3-carboxylicacid, 8-[(3S)-3-amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-,hydrochloride (1:1) 中文名: ABT-719;ABT 719;ABT719;...
中文名:ABT-719 HCl,英文名:ABT-719 HCl,CAS:162763-53-3,8-[(3S)-3-Amino-1-pyrrolidinyl]-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4H-quinolizine-3-carboxylic ac.化学式:C18H20FN3O3.HCl,分子量:381.83,MSDS.
DatasheetofABT-719HClDescription:ABT-719ive2-pyridone.ABT-719administeredorallysubcutaneously10-foldmoreeffectivethanciprofloxacinagainstStaphylococcusaureus,Streptococcuspneumoniae,Streptococcuspyogenesinfectionsnormalmice.ABT-719gram-negativebacterialinfectionscausedPseudomonasaeruginosaEscherichiacoli.ABT-719producedsimilar...
We tested ABT-719, a novel α-melanocyte-stimulating hormone analog, for prevention of AKI in postoperative cardiac surgery patients.This phase 2b randomized, double-blind, placebo-controlled trial included adult patients with stable renal function undergoing high-risk on-pump cardiac surgery in the ...
摘要: 吡啶酮类化合物ABT-719和A-170568具有抗菌谱广、抗耐药菌活性强、毒性低等特点.综述这2个候选药物的化学结构、作用机制、抗菌活性、体内安全性等药理学性质. 暂无资源 收藏 引用 分享 推荐文章 新氟喹诺酮类抗菌药ABT-492 ABT-492 氟喹诺酮 合成 药理学性质 喹诺酮类抗菌药物研究新进展 喹诺酮...
Efficacies of ABT-719 and related 2-pyridones, members of a new class of antibacterial agents, against experimental bacterial infections.: The 2-pyridones are a
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IC50of IRAK/ABT-NP was two-fold lower than free drug combination in Jurkat cells. Additionally, we conducted in vivo experiments in which IRAK/ABT-NP exhibited greater cytotoxicity toward T-ALL cells, the capacity to significantly restore white blood cell number in peripheral blood, and improved...
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