Thrombospondin-1 (TSP-1) is a pivotal endogenous anti-angiogenic regulator with actions including antagonism of vascular endothelial growth factor (VEGF) and CD36 induced cell apoptosis. It has been modified and enhanced synthetically in the form of ABT-510, a potent and novel anti-angiogenic ...
Examples of thrombospondin analogs include, but are not limited to, TSP-1, ABT-510, ABT-567 and ABT-898. Examples of aurora kinase inhibitors include, but are not limited to, VX-680, AZD-1152 and MLN-8054. An example of a polo-like kinase inhibitor includes, but is not limited to, ...
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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer. 2006;5:67. Article PubMed Central PubMed Google Scholar Glas M, Rath BH, Simon M, Reinartz R, Schramme A, Trageser D, et al. Residual tumor cells are unique cellular targets in ...
Slides were analyzed by confocal microscopy on a Zeiss LSM 510 META confocal laser microscope (Zeiss, Jena, Germany). 4.7. Mitochondrial Membrane Potential (MMP) MMP was measured using DiOC2(3) according to the manufacturer’s instructions (Invitrogen, Carlsbad, CA, USA) as we described ...
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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer. 2006;5:67. Article PubMed Central PubMed Google Scholar Glas M, Rath BH, Simon M, Reinartz R, Schramme A, Trageser D, et al. Residual tumor cells are unique cellular targets in ...
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