Analyzing patients individually confirmed the significant decrease in B cell, CD4+ T cell, and CD8+ T cell fractions in severe patients compared with the control and mild disease groups (Figure 6B), which may be a consequence of the increased neutrophil fraction (Figure 6C) and absolute numbers...
Moreover, histone H3 acetylation amount of CD8 + T cell was significantly and negatively correlated with absolute neutrophil count, proportion of reticulocytes, ratio of CD4 + to CD8 + T cell in peripheral blood, and percentage of bone marrow erythroid (P<0.05). To some extent, it also ...
An emergent blood count revealed severe leukocytopenia (1.1 3 10/ mmL with 64% lymphocytes and 4% neutrophils) and an absolute neutrophil count of 44/mmL. A Wright-stained peripheral smear revealed rare nucleated red-blood cells, granulocytopenia with normal cellular morphology, and adequate ...
Moreover, histone H3 acetylation amount of CD8(+) T cell was significantly and negatively correlated with absolute neutrophil count, proportion of reticulocytes, ratio of CD4(+) to CD8(+) T cell in peripheral blood, and percentage of bone marrow erythroid (P < 0.05). To some extent, it ...