Dr. Khaldoun Tarakji is the CMO of the Cardiac Ablation Solutions operating unit at Medtronic. The medtech giant is in theprocess of completing a global clinical trial of its PulseSelect PFA system. It’s conducting the study in the U.S. under an FDA investigational device exemption. Medtron...
Meaning This study suggests that radiofrequency ablation is a safe and efficient method to treat selected low-risk papillary microcarcinoma of the thyroid. Abstract Importance Papillary microcarcinomas of the thyroid (mPTCs) account for an increasing proportion of thyroid cancers in past decades. The ...
Meaning This study suggests that health system data are useful in postmarket evaluation of cardiovascular device safety and effectiveness. Abstract Importance The ThermoCool SmartTouch catheter (ablation catheter with contact force and 6-hole irrigation [CF-I6]) is approved by the US Food and Drug Ad...
Atrial fibrillation (AF) represents the largest disease segment, with nearly 60 million people affected worldwide.[1] AF is a progressive disease, meaning over time patients can experience more frequent, and longer episodes, and medication as well as catheter ablation can become less effective. ...
To identify software solutions presently used for evaluation of LA-ICP-MS data, we have screened the MEDLINE database for abstracts using the search terms “LA-ICP-MS” or “mass spectrometry imaging”. The search term “LA-ICP-MS” was found in 509 articles; while the search term “mass...
Alongside this aspect of psoriasis pathogenesis, and as already mentioned above, unlike in healthy skin, T cells can be found in the epidermis of psoriatic patients1, meaning that they need to cross the dermo-epithelial junction. Conrad et al. showed that epidermal but not dermal T-cells in ...
While the current definitions of AF clearly have some meaning, they are not based on detailed analyses of pathophysiologic processes or on clinically relevant outcomes. In our study, we found no significant difference in arrhythmia outcomes in patients with AF episodes limited to 24 to 48 hours ...
Meaning Among older patients with paroxysmal AF, additional LVA ablation beyond CPVI might decrease the recurrence of atrial tachyarrhythmia in older patients with paroxysmal AF compared with CPVI alone.Abstract Importance The overall success rate of circumferential pulmonary vein isolation (CPVI) treatmen...
The individual transducers910can form a phased-array, meaning that energy from multiple transducers910can work together to form a single directional beam of ultrasonic energy. This is generally performed by timing the transmission of ultrasound energy from a plurality of the transducers in order to ...
One challenge with the electrical (whether thermal or not) ablation techniques is that of local muscle stimulation. A monophasic waveform is thought to provide better results for IRE in terms of causing certain cell death. However, monophasic waveforms tend to cause muscle stimulation, requiring the...