Dosage adjustments are recommended in patients who are known CYP2D6 poor metabolizers and in patients taking concomitant CYP3A4 inhibitors or CYP2D6 inhibitors or strong CYP3A4 inducers (see Table 2). When the co-administered drug is withdrawn from the combination therapy, ABILIFY dosage should th...
Dosage adjustments are recommended in patients who are known CYP2D6 poor metabolizers and in patients taking concomitant CYP3A4 inhibitors or CYP2D6 inhibitors or strong CYP3A4 inducers (see Table 2). When the co-administered drug is withdrawn from the combination therapy, ABILIFY dosage should th...
In the three positive trials for ABILIFY, four primary measures were used for assessing psychiatric signs and symptoms. The Positive and Negative Syndrome Scale (PANSS) is a multi-item inventory of general psychopathology used to evaluate the effects of drug treatment in schizophrenia. The PANSS pos...
Increased Mortality in Elderly Patients with Dementia -Related Psychosis Use [seeBOXED WARNINGandWARNINGS ANDPRECAUTIONS] Cerebrovascular Adverse Reactions, Including Stroke in Elderly Patients with Dementia-Related Psychosis [seeBOXED WARNINGandWARNINGS ANDPRECAUTIONS] Neuroleptic Malignant Syndrome [seeWARNINGS ...
Suicidal Thoughts and Behaviors in Pediatric and Young Adult Patients [seeBOXED WARNINGandWARNINGS AND PRECAUTIONS] Cerebrovascular Adverse Events, Including Stroke [seeWARNINGS AND PRECAUTIONS] Neuroleptic Malignant Syndrome (NMS) [seeWARNINGS AND PRECAUTIONS] ...