The mutation W590S in ECD1 is associated with Tangier disease and has been studied in several laboratories (18, 57, 85., 86., 87.) and there is agreement that this variant ABCA1 reaches the PM, but exhibits defective cellular PL and FC efflux. However, there is controversy regarding ...
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However, these findings were not replicated in a large case-control study of North American subjects using either single marker or haplotype analyses (76). Further investigations will therefore be required to determine whether inactivation of ABCA1 affects AD in humans. Nevertheless, the results of ...
Proteins were transferred to 0.2 μm nitrocellulose Trans-Blot TurboTM Transfer Packs (Bio-Rad Laboratories) ®at 25 V for 10 minutes. Membranes were blocked for one hour at RT with either 5% skim milk or 5% BSA dis- solved in Tris-buffered saline (TBS) wash buffer (TBS: ...
The principal aim of LACONEU2017: 4th Latin-American Summer School in Computational Neuroscience is to promote in Latin America the field of Computational Neuroscience through cutting edge mathematical and computational science tools and its applications in Biomedical Research and Clinical Application. The...
VC 2012 American Neurological Association 53 ANNALS of Neurology induced by myelin-specific T cells.4,5 T cells are detected within active NMO lesions.6 Further, NMO lesions are characterized by an abundance of eosinophils and neutro- phils, and elevated levels of IL-17 h...
C. lusitaniae isolates were grown in complete medium Yeast Extract Peptone Dextrose (YEPD) (1% Bacto peptone, Difco Laboratories, Basel, Switzerland), 0.5% yeast extract (Difco) and 2% glucose (Fluka, Buchs, Switzerland) at 30 °C under agitation. YEPD agar plate were used containing 2% agar...
Human THP-1 monocytes were originally obtained from American Type Culture Collection (Manassas, VA, USA). THP-1 cells were grown in RPMI-1640 medium supplemented with 10% FBS, 100 IU/mL penicillin and 10 μg/mL streptomycin. Cells were maintained in a humidified incubator at 37 °C with ...
327 American Generics S.A.S. 子公司 100.00% 328 Abbott Laboratories, Ireland, Limited 子公司 100.00% 329 Tendyne Medical, Inc. 子公司 100.00% 330 Abbott Resources Inc. 子公司 100.00% 331 Abbott Diagnostics Investments B.V. 子公司 100.00% 332 Abbott Mature Products Management Limited 子公司 10...
Photodynamic therapy (PDT) is a cancer treatment that make use of the cancer-specific accumulation of porphyrins. We have reported that mitochondrial reactive oxygen species (mitROS) upregulate uptake transporter of porphyrins, heme carrier protein-1 (HC