Since 2010, the standard of care for patients with unresectable BTC is palliative treatment with gemcitabine plus cisplatin, based on the landmark phase III ABC-02 trial. This current study aims to evaluate the efficacy and safety of gemcitabine and cisplatin in patients with unresectable ...
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CONCLUSION: First-line gemcitabine and cisplatin is an effective and safe treatment for patients with unresectable BTC who do not meet the eligibility criteria for the ABC-02 trial. Median OS, PFS and treatment side effects were comparable between the patients who received chemotherapy (group I vs...
心房颤动(简称房颤)是临床上最常见的持续性心律失常,其可显著增加房颤患者心力衰竭及缺血性脑卒中的发生风险,有研究显示房颤患者缺血性脑卒中发生风险是一般人群的5倍。目前临床上常用CHADS2及CHA2DS2-VASc评分量表来为房颤患者进行缺血性脑卒中的危险分层。 然而,CH...
[29] Rugo HS, et al. Health-related quality of life (HRQoL) in the phase III TROPiCS-02 trial of sacituzumab govitecan (SG) vs chemotherapy in HR+/HER2- metastatic breast cancer (MBC). 2022ESMO Abstract #1553O. *此文仅用于向医学人士提供科学信息,不代表本平台观点...
Judge says Elon Musk's claims of harm from OpenAI are a 'stretch' but welcomes possible trial Elon Musk’s lawyers faced off with OpenAI in court Tuesday as a federal judge weighed the billionaire’s request for a court order that would block the ChatGPT maker from converting itself to a...
The ABC-02 trial has defined the standard therapy for patients with advanced biliary tract cancer (ABC); however, outcome in an unselected patient population in the UK has not been described. We aimed to investigate the outcome of a series of patients with ABC from two large UK cancer networ...
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