This trial has several limitations, including the fact that it only involved Chinese subjects and did not include patients with keratinizing tumors due to their rarity in China. Furthermore, only 2 elderly patients (≥65 years) were included. The efficacy and safety profile of penpulimab in pa...
Primaryadrenal insufficiency(PAI) has also been reported with ICI therapy. Polymorphism of the CTLA-4 gene has been associated with the development of this entity.43,44Due to its rarity, there are no studies to our knowledge which have thoroughly evaluated its pathogenesis. ...
The rarity of GPP and lack of large-scale clinical tri- als pose challenges in finding evidence-based therapeutic options. Current management of GPP flares often relies on conventional systemic therapies used for moderate to severe plaque psoriasis, with retinoids, cyclosporine and methotrex- ate ...
Due to the rarity of advanced stage NKTCL, one limitation of the study is the modest sample size and relatively short follow-up. Nevertheless, the optimal response rate and survival observed in this study have provided substantial evidence to initiate a multicenter, prospective, randomized clinical ...
with a median age of diagnosis of 55 years. Considering the rarity of the indication, the phase III that led to the approval of MP consisted of a single arm trial. Patients aged > 65 years old had fewer durable Complete Responses (CR) than younger patients (2/31 vs 22/49 respectively...
This type of cancer is recognized for its rarity which comprises less than 1% of male malignancies worldwide [1,2]. SCC accounts for the majority of cases of penile cancer [19]. The exact cause of penile cancer remains incompletely understood. pSCC can originate from penile intraepithelial ...
Research shows that millennials have a strong interest in products that offer authenticity, rarity and preciousness – and a billion-year-old diamond is an ideal expression of authenticity in their lives and relationships. 在这个飞速发展的、工业文明高度发达...
different color entirely from the rest of the iris due to pigmentation differences. It’s quite an interesting type of eye coloring that some individuals have, and while many people wear contacts in order to make their color more uniform. I think it’...
//0xF8 + WORD wMissileType; //0xFA + BYTE nRarity; //0xFC + BYTE nLevel; //0xFD + BYTE nMinDam; //0xFE + BYTE nMaxDam; //0xFF + BYTE nMinMisDam; //0x100 + BYTE nMaxMisDam; //0x101 + BYTE n2HandMinDam; //0x102 + BYTE n2HandMaxDam; //0x103 + WORD wRangeAdder;...
BLOOD_SPELL_DAMAGE = { key: 'irons_spellbooks:blood_spell_power', name: 'kubejsBloodSpellDamage', operation: 'addition' } 31 32 32 33 global.ATTRIBUTE_MAP = { 33 34 'kubejsAttackDamage': global.ATTACK_UP, @@ -52,6 +53,7 @@ global.ATTRIBUTE_MAP = { 52 53 'kubejs...