2.SHR心肌转染的效应:(1) Real-time RT-PCR结果显示,AAV9-shRNA-ADRB1-ZsGreen注射后β1-AR mRNA表达明显低于阴性对照组(0.4142±0.3399vs.1.0933±0.5853,P0.05);(2)免疫组化结果显示,AAV9-shRNA-ADRB1-ZsGreen注射后β1-AR蛋白表达明显低于阴性对照组及假手术组(50.02±4.44vs.80.05±3.72vs.79.30±2.79...
Intraperitoneal administration of AAV9-shRNA inhibits target gene expression in the dorsal root ganglia of neonatal mice. Machida A,Kuwahara H,Mayra A, et al. Mol Pain . 2013Machida A, Kuwahara H, Mayra A, Kubodera T, Hirai T, Sunaga F, Tajiri M, Hirai Y, Shimada T, Mizusawa H, ...
AAV9-shRNA (ssAAV9-shRNA) intraperitoneally to neonatal mice and sufficiently inhibited a target gene in the DRG without any side effects. We chose superoxide dismutase 1 (SOD1) as the target gene because it is an appropriate endogenous gene for evaluating the side ...
In this unit, we describe protocols for use of rAAVs as a cargo to deliver miRNA backbone-based shRNA controlled by a cardiac-specific promoter into the mouse heart. 漏 2016 by John Wiley & Sons, Inc.HirokoWakimotoJ GSeidmanRoger S Y...
采购单位: *** 采购时间: 2024-12-11 13:03:07 采购备注: 无 使用币种: 人民币 采购类型: 线上单 经费负责人审批时间: 2024-12-11 供应商 商品名称 货号 规格 单价 数量 总价 *** Plaur基因shRNA AAV9型 202***6010 1ml 10300.00 1 10300.00 招标进度跟踪 2024-12-11 招标公告药学院Plaur基因sh...
Intraperitoneal AAV9-shRNA inhibits target expression in neonatal skeletal and cardiac muscles. Biochem Biophys Res Commun. 2011; 405(2):204-209. [PubMed: 21219850]Mayra A, Tomimitsu H, Kubodera T, et al. Intraperitoneal AAV9- shRNA inhibits target expression in neonatal skeletal and cardiac...
In this unit, we describe protocols for use of rAAVs as a cargo to deliver miRNA backbone‐based shRNA controlled by a cardiac‐specific promoter into the mouse heart. © 2016 by John Wiley & Sons, Inc.doi:10.1002/cpmb.9Hiroko Wakimoto...
Systemic delivery of sh RNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart,but not liver. Piras BA,O’’Connor DM,French BA. PLo S One . 2013Piras BA, O'Connor DM, French BA (2013) Systemic delivery of shRNA by AAV9 provides highly efficient ...
GW27-e0227 Downregulation of the β1 adrenergic receptor in myocardium by AAV9-shRNA-ADRB1-ZsGreen injection reduce blood pressure in spontaneously hypertensive ratsGaiyanWenYuanHongingentaconnectJournal American College of Cardiology
GW27-e0227 Downregulation of the β1 adrenergic receptor in myocardium by AAV9-shRNA-ADRB1-ZsGreen injection reduce blood pressure in spontaneously hypertensive ratsThis paper describes a new portable real-time remote electrocardiography (ECG) monitor based on mobile communication technology. ...