▲2021年8月-2022年7月FDA新批准的抗癌疗法(图片来源:AACR官网)其中,靶向疗法可以更为精准地针对肿瘤中的癌细胞,从而让治疗更为有效,并且降低对健康组织的毒性。而且,这些靶向疗法,为治疗罕见癌症提供了有力的手段。罕见癌症虽然发病率不高,但是种类繁多,根据美国国家癌症研究所(NCI)的统计,美国的癌症死亡...
医药魔方-2022+AACR+新药开发机会分析-20220413-Final.pdf,2022 AACR 新药开发机会分析 April 8 - 13, 2022 新药数据部 2022.04.13 NextPharma全球新药数据库:聚焦临床开发数据 加速新药情报获取 管线产品检索 药品/靶点联用检索 成熟、积极、消极靶点 按技术、区域、作用
AACR年会是世界规模最大的癌症研究会议之一,汇集了癌症领域最前沿 的研究成果,2022 AACR年会于美国中部时间4月8日-13日在新奥尔良 举行 • 医药魔方关注首次在论文/会议上报道的药物分子,对2022 AACR 会议 摘要进行筛选,共收录251篇摘要 • 基于 NextPharma® 数据库 - 转化医学模块(早期靶点发现)和 PharmaInve...
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5leadingtovarioustumorcellintrinsiceffectsandtumorregressionsinmouseAACR2022RibonTherapeutics models Abstract381:ElevatedPARP7expressioninselectcancersidentifiesatarget 6AACR2021RibonTherapeutics populationforRBN-2397therapy AbstractDDT02-01:RBN-2397:Afirst-in-classPARP7inhibitortargetinga ...
inhibitor RBN-2397 in patients with selected advanced solid tumors AACR 2023 Ribon Therapeutics 5 Abstract 2154:PARP7 inhibitor 25、 RBN-2397 increases tumoral IFN signaling leading to various tumor cell intrinsic effects and tumor regressions in mouse models AACR 2022 Ribon Therapeutics 6 Abstract ...
BT5528, a Bicycle Toxin Conjugate (BTC) targeting EphA2 has potent anti- tumour activity without bleeding or coagulation abnormalities in animal models Gavin Bennett1, Philip Huxley1, Amy Brown1, Gemma Mudd1, Peter U. Park2, Nicholas Keen2. ABSTRACT# 5854 WHY BICYCLES RESULTS Novel Drug...