An A549 lung carcinoma-bearing model was established by subcutaneous injection of A549 cells at a concentration of 5 × 106 cells/mouse into the right front flank of the mice. SPECT planar imaging. SPECT planar imaging was performed when the tumor volume was approximately 1 cm3. ...
The present study represents the first time that celecoxib, a special COX-2 inhibitor widely used in clinics, was explored to normalize the tumor microenvironment and to improve tumor nanotherapeutics delivery using a human-derived A549 tumor xenograft as the solid tumor model. Immunofluorescence ...
Fig 4. Tumor growth curve of A549 xenograft model in hPBMC (M-NSG) mice. (n=6) Figure 5. Body weight change of A549 xenograft model in hPBMC (M-NSG) mice. (n=6) 野生型细胞株不进行出售服务,仅作为荷瘤鼠和体内药效进行服务。
Lung cancer modelVaccinating densityTumor growthOrgan metastasisLung metastasis of malignant tumors, such as lung carcinoma, is a major cause of cancer-related deaths worldwide. The commonly used lung tumor models were established by subcutaneous or intravenous injection of the non-small cell lung ...
Objective:To build a moderate lung cancer orthotopic transplantation tumor model,and to investigate the expression of metabolic pathway in the this model. Methods:After optimizing the dose of anesthetic medicine and operation procedures of endotracheal orthotopic transplantation,5×106 of A549 cells were ...
采用Western blot检测SAPCD2在肺癌细胞与正常肺上皮细胞中蛋白表达,选取SAPCD2蛋白表达最高的细胞株进行实验,通过检测转染后细胞的SAPCD2蛋白表达水平明确该细胞的转染效率。通过检测增殖相关蛋白ki-67、Bcl-2,凋亡相关蛋白Caspase-3以及Hippo信号通路相关蛋白NF2、P-MST1、P-LATS1、P-YAP、YAP、TAZ在NC组、si-SAPCD...
展开更多 Objective To verify the anti-tumor effect of the mesenchymal-epithelial transition single-chain antibody(Met scFv)on subcutaneously transplanted tumors in nude mice.Methods A tumor model was established in nude mice by subcutaneous injection of A549 lung adenocarcinoma ...MORE 作者 安然 ...
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer. Cell. Immunol. 175:101-110(1997) PubMed=9178645; DOI=10.1006/cimm.1997.1108 Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M., Itoh K. ...
The following options are typically available for an A549 CDX xenograft model: •Dosing frequency and duration of dose administration •A549 Tumor Growth Delay •A549 Tumor Growth Inhibition •Dosing routes: ·Intravenous ·Intratracheal
After 18 days of continuous administration ,the body weight of mice and the mass of the transplanted tumor were detected and the tumor inhibition rate was calculated. Human lung cancer cells A 549 and A 549/DDP were collected and divided into normal group (A549 cells),control group (A549/...