A series of new anthracene﹑ropargylamine derivatives were obtained through an efficient synthesis based on the A3 coupling reaction. This set of planar molecules were designed to bind double stranded and G﹒uadruplex DNA arrangements. Their interaction pattern of the small molecules with DNA was ...
Yuan, WeimingMa, ShengmingNat CommunNature CommunicationsFan, W.; Yuan, W.; Ma, S. Unexpected E-stereoselective reductive A(3)-coupling reaction of terminal alkynes with aldehydes and amines. Nat. Commun. 2014, 5, 3884. [CrossRef] [PubMed]...
A3-couplingmicrowave chemistrymulticomponent reactionspropargylaminessynthetic methodsThree-component coupling reaction: An efficient, microwave-assisted, CuI-catalysed A3-coupling reaction with primary aliphatic amines that gives access to secondary propargylamines is described (see scheme).doi:10.1002/chem....
一、J.J. Li, Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications, Chan–Lam C–X coupling reaction,page 125-127. 二、https://www.organic-chemistry.org/namedreactions/chan-lam-coupling.shtm
Efficient Preparation of the Isoindoline Framework via a Six Component, Tandem Double A3‐Coupling and [2+2+2] Cycloaddition Reaction The preparation of tetrasubstituted isoindolines from three alkyne units, two aldehyde units and a primary amine via three consecutive reactions, two ald... ER Bonfi...
become as much dependent on the ability to purify and characterize the product of the coupling reaction as on the chemistry of the coupling reaction ... Z Xu,M Kahr,KL Walker,... - 《Journal of the American Chemical Society》 被引量: 427发表: 1994年 Synthesis of Symmetrical and Unsymmetri...
二、化学空间:http://www.chem-station.com/cn/?p=1691 三、Organic Chemistry Portal:https://www.organic-chemistry.org/namedreactions/pinacol-coupling-reaction.shtm 定制合成征询 2,3-dihydroxy-2,3-dimethylbutanedioic acid(不需要手性提纯) (cas号74543-88-7...
Taxol-stabilized microtubules were incubated at room temperature for 10 min with 1 μM protein in a 50 μl reaction volume in BRB80 buffer (80 mM PIPES pH 6.9, 1 mM EGTA, 1 mM MgCl2) with 100 mM NaCl and 4 mM DTT in the presence of 50 μM taxol. The ...
The LFE and TFE piezoelectric coupling factors of thickness-shear modes (b, c) of the (yxl)-6° CTGS plate were calculated using the extended Christoffel-Bechmann method [20], which is highly efficient in calculating the piezoelectric coupling factors. Here, b and c correspond to the fast-...
2) palladium-catalysed cross-coupling reaction Pd催化偶联反应 1. In palladium-catalysed cross-coupling reaction of aniline iodide and N,N-Dimethyl butyryl silane,reaction condition was strict because of needed-78℃. 在早期的合成方法中,Fischer吲哚反应产率很低;在由碘代胺与酰基硅烷经Pd催化偶联反应...