Example of capillaries labelled with PECAM1 antibody (green) in a skeletal muscle tissue (α-sarcomeric actin antibody, red).Barbara RinaldiMaria DonniacuoLoredana SodanoGiulia GrittiSimona SignorielloElisabetta ParrettaLiberato BerrinoKonrad UrbanekAnnalisa Capuano...
Fig. 5. Immunofluorescence analysis of skeletal muscle to detect telethonin (red), actin (green, left) and myosin (green, centre). The three frames on the left (a, b, c) show the same field of a section of human skeletal muscle where rhodamine (red) corresponds to telethonin while flu...
The model for disordered actomyosin bundles recently derived by Oelz, in the work 'A viscous two-phase model for contractile actomyosin bundles' (Math. Biol., 68 (2013), 1653--1676) includes the effects of cross-linking of parallel and anti-parallel actin filaments, their polymerization and...
Below: corresponding FI profile of NMIIC (green), actin (red), and α-actinin1 (blue). Scale bars represent 10 μm in (A) and 3 μm in (B)–(E). See also Figure S1. Because our data support a role for NMII in modulating epithelial apical perimeter we sought to assess the ...
A note on immunohistochemical staining for sarcomeric actin in rhabdomyosaecoma and other round cell tumors. Carter RL,Hall JM. Histopathology . 1992Carter RL, Hall JM: A note on immunohistochemical staining for sarcomeric actin in rhabdomyosarcomas and other round cell tumours. Histopathology 1992,...
In this mini-review, we summarized isoform transitions of several most widely examined sarcomeric proteins including myosin, actin, troponin, tropomyosin, titin and myosin binding protein-C, and the consequence of these abnormal isoform transitions. Even though the isoform transitions of sarcomeric ...
actinα-actininArgBPvinculinArgBP2 (Arg/Abl-Binding Protein) is expressed at high levels in the heart and is localized in the Z-bands of mature myofibrils. ArgBP2 is a member of a small family of proteins that also includes vinexin and CAP (c-Cbl-associated protein), all characterized by...
Among variants in the linkage peaks we recovered a novel heterozygous 3-bp inframe deletion in alpha-tropomyosin, TPM1, an actin-binding protein. This variant causes deletion of a conserved amino acid (p.K5del) and showed complete segregation with ASD. It was absent in >700 CHD cases and ...
GST-ArgBP2-SH3 bound actin, alpha-actinin and vinculin proteins in blot overlays, cosedimentation assays, and EM negative staining techniques. Over-expression of ArgBP2 and ArgBP2-SH3 domains, but not YFP alone, led to loss of myofibrils in cardiomyocytes. Fluorescence Recovery After ...
Kedes. Identification and characterization of a factor that binds to two human sarcomeric actin promoters. J. Biol. Chem. 264: 1284- 1292, 1989.Boxer L, Miwa T, Gustafson T, Kedes L (1989) Identification and characterization of a factor that binds to two human sarcomeric actin promoters. ...