to mature skeletal muscle upon intravenous vector administration (1), the current generation of vectors has nonetheless found utility in preclinical studies of gene therapy and in gene-transfer experiments designed to study muscle biology. Fe... JT Douglas - 《Methods in Molecular Biology》 被引量...
The time surrounding Ross' epic studies on the role mosquitoes play in the life cycle of Plasmodium was marked by a series of discoveries that truly defined the beginning of the field of vector biology, as outlined here by Bruce Christensen and Michael Ferdig....
This is a list of implementations of deep learning methods to biology, originally published onFollow the Data. There is a slant towards genomics because that's the subfield that I follow most closely. Please, contribute to this growing list, especially in categories that I haven't covered well...
Adeno-associated virus structural biology as a tool in vector development. Future Virol. 8, 1183–1199 (2013). CAS PubMed PubMed Central Google Scholar Duan, D. et al. Dynamin is required for recombinant adeno-associated virus type 2 infection. J. Virol. 73, 10371–10376 (1999). CAS ...
Vector containing a chicken beta-actin gene promoter for the expression of a desired gene An expression vector for the expression of a desired gene in an animal cell is described, which contains a chicken 尾-actin gene promoter or a derivative thereof and downstream thereof a restriction enzyme ...
IgG (Abcam, ab205718) and goat polyclonal antibodies conjugated to HRP (DAKO, K4003; Vector Lab, PI-1000). Enzyme-linked immunosorbent assay kits ELISA kits used were as follows: IL-1β (Sinobest Bio, YX-E01291M), IL-4 (Sinobest Bio, YX-E00064M), IL-6 (Sinobest Bio, YX-E00066...
[1] Santry L A , Ingrao J C , Yu D L ,et al.AAV vector distribution in the mouse respiratory tract following four different methods of administration[J].Bmc Biotechnology, 2017, 17(1):43. [2] Sandhya D,Kelvin M,Sucie H C, et al. A simple method of mouse lung intubation.[J]....
In vivo pre-targeting achieves this by decoupling the targeting vector and radioactivity, administering the two components separately, and allowing them to be coupled within the body. Due to the high reaction rate (k2 up to 106 M−1 s−1), non-metallic nature, and physiological pH, the ...
(2) computing protein sequence representation by a pretrained protein language model named TAPE-BERT, (3) replacing 1D convolutional neural networks and gated linear units with a self-attention-based transformer encoder, and (4) introducing a new atom vector into the atom sequence that carries the...
The vector flow in a uniform manifold approximation and projection (UMAP) embedding of the transcriptome clearly suggests that cellDancer recaptures the progression of erythroid differentiation (Fig. 2a, top), whereas scVelo’s prediction was reversed18 (Fig. 2a, bottom). Fig. 2: Delineating ...