DNA四大天王－A、G、T、C DNA是很长的分子链，由四种盐基组成，分别是腺嘌呤（A adenine）、鸟粪嘌呤（G guanine）、胞嘧啶（C cytosine）及胸线嘧啶（T thymine）。每一对盐基不是 A T就是G C。在DNA的两条链结合 时，A必定和T结合，G必定和C结合，其他的组合无法衔接这两条锁链。因为A和T...
根据碱基互补配对的原则，一条链上的A一定等于互补链上的T；一条链上的G一定等于互补链上的C，反之如此。因此，可推知多条用于碱基计算的规律。规律一：在一个双链DNA分子中，A=T、G=C。即：A+G=T+C或A+C=T+G。也就是说，嘌呤碱基总数等于嘧啶碱基总数，各占全部碱基总数的50%。规律二：在双链DNA...
The solution structure of the DNA analogue of the unusually stable r[C(UUCG)G] RNA hairpin, 5'-d[GGA-C(TTCG)GTCC]-3', has been determined by NMR spectroscopy, and its structure has been compared to that of the RNA molecule. The RNA molecule is compact and rigid with a highly str...
Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator Andreas Schlundt, Sophie Buchner, Robert Janowski, Thomas Heydenreich, Ralf Heermann, Jürgen Lassak, Arie Geerlof, Ralf Stehle, Dierk Niessing, Kirsten Jung & Michael Sattler Scientific...
The application of detailed structural data bases has now culminated in the successful design of a new generation of bisanthracyclines that form ultratight DNA complexes [Chaires, J. B., Leng, F., Przewloka, T., Fokt, I., Ling, Y. H., Perez-Soler, R., & Priebe, W. (1997) J....
The structure has two-fold symmetry, with pairwise stacking of the double-helical arms, which form two continuous B-DNA helices that run antiparallel, cross in a right-handed way, and contain two G-A mismatches. The exchanging backbones form a compact structure with strong van der Waals ...
Donor DNA sequnece for Flag-Toc34 KI:AACCGCTTAGACTACAAGGACCATGACGGTGACTATAAGGATCACGACATCGACTACAAGGACGATGACGACAAGCCGGTATGTGGGGTG This paper N/A Recombinant DNA Pre-RbcS2 cloned into a modified pET21 vector with C terminal Protein A-His tag This paper N/A Software and algorith...
These structures represent the first full-length functional tetrameric protein in complex with its intact DNA operator containing two continuous recognition sites. TtgV binds to its DNA operator as a highly asymmetric tetramer and induces considerable distortions in the DNA, resulting in a 60° bend...
known as aphosphate groupattached to the sugar molecule (Figure 1). There are four different DNA nucleotides, each defined by a specific nitrogenous base:adenine(often abbreviated "A" in science writing),thymine(abbreviated "T"),guanine(abbreviated "G"), andcytosine(abbreviated "C") (Figure 2...