Lyme disease is a multi-systemic infection caused by the spirochaete Borrelia burgdorferi: this bacterium, discovered in 1982 in the United States, is mainly transmitted by a tick bite, Ixodes ricinus in Europe. In Belgium, a first seroe... G Bigaignon - 《Bulletin Et Mémoires De Lacadé...
This biosynthetic pathway involves three enzymes: a tetra-naphthalene reductase, a scytalone dehydratase, and a 3HN reductase. These proteins are encoded, respectively, by the HNR4, RSY1, and BUF1 genes. Knockout of these genes led to a loss of the function of appressorium-mediated ...
One major role of VDAC1 involves regulation of the release of mitochondrial pro-apoptotic proteins such as cytochrome c (cyto c), from the intermembrane space (IMS) to the cytosol, and apoptosis regulation via interactions with apoptosis regulatory proteins such as Bcl-2, Bcl-xL, and hexokinase...
Sepsis is a syndrome that arises when the body’s response to a severe infection injures its own tissues. In 1992 an international consensus panel proposed a clinical definition for sepsis, making use of the concept of a “systemic inflammatory response syndrome” (SIRS), involving alterations in...
Another potential mechanism through which diet could increase inflammation within the hypothalamus involves the gut microbiota. It has been proposed that high-fat diets alter the composition of the gut microbiota, which in turn leads to increased intestinal permeability and systemic exposure to bacterial...
In recent years, obesity has become a worldwide epidemic characterized by an increased body composition of adipose tissue. The association between obesity and OA has long been recognized.41,42 Patients with obesity develop OA earlier and have more severe symptoms, higher risk for infection and more...
In this experimental model, neither nutritional status (determined via measurements of plasma cholesterol, protein and lipids) nor whole-body weight gain at the end of the study period is significantly different between CS-exposed and sham animals [16]. Moreover, no changes in the proportion of ...
Influenza virus infection is among the most detrimental threats to the health of humans and some animals, infecting millions of people annually all around the world and in many thousands of cases giving rise to pneumonia and death. All those health crise
Systemic in- fection by fusarium in a burned child: the emergence of a saprophytic strain. J Pediatr 1974; 84:561-4.Abramowsky, C. R., Quinn, D., Bradford, W. D., and Conant, N. F. Systemic infection by Fusarium in a burned child. J. Pediatr ., 84, 561, 1974....
Fig. 1: SpeB-mediated gasodermin A cleavage triggers pyroptosis in skin epithelial cells and prevents systemic dissemination of group A streptococci in mice. ASkin infection of wild-type mice with SpeB+GAS induces local skin inflammation, and bacteria are contained at the site of infection. No...