For the students, perceived personal risk was influenced most by perceived risk to male friends and people with the same sexual practices, whereas for the community samples it was influenced most by perceived risk to people with the same practices. The results suggest a strong peer influence on perceptions of personal risk of HIV infecti...
This biosynthetic pathway involves three enzymes: a tetra-naphthalene reductase, a scytalone dehydratase, and a 3HN reductase. These proteins are encoded, respectively, by the HNR4, RSY1, and BUF1 genes. Knockout of these genes led to a loss of the function of appressorium-mediated ...
BMC Infectious Diseases (2019) 19:34 https://doi.org/10.1186/s12879-018-3621-8 CASE REPORT Open Access Severe systemic cytomegalovirus infection in an immunocompetent patient outside the intensive care unit: a case report Giovanni Carpani1* , Sergio Foresti2, Raffaella Dell'Oro1, Guido Grassi...
Pan-viral signature in models of infection involving DNA viruses. Panel (A): Adenovirus (double-stranded DNA; Baltimore group I). Pan-viral signature measured in liver tissue derived from wild-type or C3-knockout mice injected with phosphate buffered saline (mock) or adenovirus type 5 capsids ...
This presence of a too diverse microbiota in the very early life involves a disproportionate short-chain fatty acids ratio and an excessive antigen exposure across the vulnerable gut barrier in the first days of life, before the gut closure. Besides, as shown by microbiota transfer experiments, ...
Sepsis is a syndrome that arises when the body’s response to a severe infection injures its own tissues. In 1992 an international consensus panel proposed a clinical definition for sepsis, making use of the concept of a “systemic inflammatory response syndrome” (SIRS), involving alterations in...
Fig. 1: SpeB-mediated gasodermin A cleavage triggers pyroptosis in skin epithelial cells and prevents systemic dissemination of group A streptococci in mice. ASkin infection of wild-type mice with SpeB+GAS induces local skin inflammation, and bacteria are contained at the site of infection. No...
A major critique of the 'glymphatic' hypothesis involves the proposed role of AQP4. Aquaporins are a large family of cell membrane channels containing ~ 0.5 nm pores [72] that confer selective permeability to water and, in some cases, certain other small molecules; AQP1, AQP4, AQP5, ...
In recent years, obesity has become a worldwide epidemic characterized by an increased body composition of adipose tissue. The association between obesity and OA has long been recognized.41,42 Patients with obesity develop OA earlier and have more severe symptoms, higher risk for infection and more...
While it has been shown that in clams the bacteria are acquired vertically, in mussels this occurs horizontally and most likely by means of a continuous process during the whole lifetime of the host (Wentrup et al., 2014). Alviniconcha is one of the few examples of marine invertebrates ...