本实验采用双抗体夹心ABC-ELISA法。用抗人a-Synuclein单抗包被于酶标板上,标准品和样品中的a-Synuclein与单抗结合,加入生物素化的抗人a-Synuclein,形成免疫复合物连接在板上,辣根过氧化物酶标记的Streptavidin与生物素结合,加入底物工作液显蓝色,最后加终止液硫酸,在450nm处测OD值,a-Synuclein浓度与OD值成正比,可通过...
新产品1: Human alpha-Synuclein 验证样本类型: cell culture supernatant, serum, plasma (EDTA/Heparin), cerebrospinal fluid (CSF) 指标简介: Alpha-synuclein(α-突触核蛋白,简称a-syn)是一种主要存在于神经元突触前末端的蛋白质,特别是那些富含囊泡的区域。它在正常情况下与细胞膜结合,并参与调控突触小泡的循...
This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of A-SNCO (hereafter termed "analyte") in undiluted original Human body fluids, tissue ...
α-synuclein与帕金森病 帕金森病(PD)因其临床常表现为震颤、肌强直、运动迟缓等,又被称为震颤麻痹,它的病因有十多种,包括遗传因素、环境因素、老化、病毒或细菌感染等等,而α-synuclein(一种突触前末梢蛋白)主要与遗传性PD相关。 在上世纪末,科学家们发现家族性PD与α-synuclein基因的第四号外显子错义突变存在...
直立角茴香碱HPLC≥95% 20mg Ratglucocoicoidreceptor,GRELISA试剂盒大鼠糖皮质类受体(GR)ELISA试剂盒规格:96T/48T 突触核蛋白英文名称:HumanαSynucleinα规格:48T/96T英文缩写:α-SYN 4-Amino-2,5-dimethoxy-N-phenylbenzenesulphonamide 52298-44-9中文名:4-氨基-2,5-二甲氧基-N-苯基苯磺酰胺分子式:C14H16...
ELISABiomarkerA recently developed conformation-specific ELISA can detect aggregated forms of α-synuclein in human erythrocytes.Aggregated, but not total, α-synuclein is elevated in erythrocytes from PD patients compared to controls.The accumulation of α-synuclein aggregates in erythrocytes is not due...
A-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). A-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it h
A-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). A-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it h
Human αN-acetylglucosaminidase,αNAG ELISA试剂盒 质量规格:>95%,BR Ac-YVAD-pNA Human α-sarcomeric actin,α-SCA ELISA试剂盒 质量规格:>95%,BR ACTH (1-10), human Human α-Smooth muscle actin,α-SMA ELISA试剂盒 质量规格:>95%,BR ACTH (1-13), human Human α-Synuclein,α-SYN ELISA试剂...
确定可靠的诊断和预后的帕金森病(PD)的生物标志物是迫切需要的。在这里,作者探索了血浆神经元外泌体中的a-synuclein (a-syn)作为PD早期诊断和疾病进展的生物标志物的潜在用途。 本研究包括横断面和纵向设计。研究对象包括36例早期PD患者、17例晚期PD患者、20例特发性快速眼动睡眠行为障碍患者和21例健康对照组(HCs...