This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance ...
The abilities of an organism to cope with extrinsic stresses and activate cellular stress responses decline during aging. The signals that modulate stress responses in aged animals remain to be elucidated. Here, we discover that feeding Caenorhabditis el
In this context, the field of bone tissue engineering (BTE) aims at developing new strategies to render scaffold platforms that mimic not only the structure and composition of the ECM but also its functionality. Such a challenge is achieved by embedding a wide range of bioactive agents such as...
Coronavirus (SARS-CoV-2), the cause of COVID-19, a fatal disease emerged from Wuhan, a large city in the Chinese province of Hubei in December 2019. The World Health Organization declared COVID-19 as a pandemic due to its spread to other countries inside
et al. Newborn metabolomic signatures of maternal per- and polyfluoroalkyl substance exposure and reduced length of gestation. Nat. Commun. 14, 3120 (2023). Article CAS PubMed PubMed Central Google Scholar Feng, H. et al. Association of nutrients intake during pregnancy with the risk of ...
In addition, the fatal killer of H1N1, H5N1 and H7N9, as well as Ebola virus, is also proven to be a cytokine storm, which triggers the immune system to violently attack the body's tissues and organs [57,58,59]. Treatment of cytokine storm On January 30th, 2020, the first guidelines...
Triple therapy in the management of chronic obstructive pulmonary disease: systematic review and meta-analysis. BMJ. 2018;363:k4388. doi:10.1136/bmj.k4388PubMedGoogle ScholarCrossref 63. Zhang L, Huang G, Jin L, Han S. Therapeutic effects of a long-acting cholinergic ...
Low-temperature stress is one of the conditions that triggers sexual reproduction in fungi [82]. In the initial stage of low-temperature stress, mannitol in Volvariella volvacea was largely decomposed as an energy substance, and synthesis-related enzymes were inhibited. However, after long-term ...
Alcohol use disorder (AUD) is the most prevalent substance use disorder worldwide [1]. Most AUDs remain untreated [2] and for those seeking treatment, relapse rates are high [3]. Adolescence marks a rapid increase in AUD and an earlier onset of AUD is associated with worse long-term outco...
Here we report the development and preclinical therapeutic performance of a strain-programmed patch that rapidly and robustly adheres to diabetic wounds, and promotes wound closure and re-epithelialization. The patch consists of a dried adhesive layer of crosslinked polymer networks bound to a pre-...