In this paper a normal form, called Separated Normal Form (SNF), for temporal logic formulae is described. A simple propositional temporal logic, based on a discrete linear model structure, is introduced and a procedure for transforming an arbitrary formula of this logic into SNF is described....
cerevisiae Snf3p and Rgtp proteins have longer C-terminal tails than their parologous Hxt (hexose transporter) counterparts, Hxt1p-Hxt17p and Gal2p. It has been suggested that the longer tail is involved in their glucose sensing functions, especially since they do not transport glucose (...
63. We also know that MyoD binds DNA as an inactive form in proliferating myoblasts64. Based on these data, it is possible that the small observed difference of chromatin loops between WT andMyoD-null myoblasts might reflect a lack of MyoD-regulated transcription in the myoblasts if the format...
LncRNAs have been shown to be direct players in chromatin regulation, but little is known about their role at active genomic loci. We investigate the role of lncRNAs in gene activation by profiling the RNA interactome of SMARCB1-containing SWI/SNF complexes in proliferating and senescent conditions...
While it is possible to at least define the exact size of these fields in scientific publications, this does not allow an accurate grade to be assigned in routine practice. It is arguable that there is little excuse for the use of HPFs, when international standard (SI) units such as mm2 ...
some preclinical studies using the CRISPR screen technique have elucidated the mechanism of action of PBRM1 and SGOL1 in cancer drug resistance. PBRM1 is a SWI/SNF complex subunit. This complex is involved in altering the nucleosome position and controlling chromatin availability and appears to have...
2.1 Rank 1 The basis of our model is a version of the SM where the two light generations of left-handed fermions form doublets under a new gauge symmetry SU(2)q+ . The charges of the fields are detailed in Table 1. We anticipate having to break the new symmetry at a high energy ...
CopyKAT - CopyKAT (Copynumber Karyotyping of Tumors) is a computational tool using integrative Bayesian approaches to identify genome-wide aneuploidy at 5MB resolution in single cells to separate tumor cells from normal cells, and tumor subclones using high-throughput sc-RNAseq data. Paper Ruli ...
This work is part of the Zurich Heart project under the umbrella of "Hochschulmedizin Zürich" and is supported by the Stavros Niarchos Foundation. This work is also supported by funding from the Swiss National Science Foundation (SNF), Grant 205321_188828. Appendix A. Supplementary data Download...
We also found that TRIM29 binds PRMT1 and the SWI/SNF complex (Fig. 2j), which both have clear roles in transcriptional regulation. SCLC accounts for approximately 15% of lung cancer and is a highly malignant and nearly uniformly fatal disease. To date, no targeted therapy has been ...