A restricted cubic spline approach to assess the association between high fat fish intake and red blood cell EPA + DHA content. Nutr Metab Cardiovasc Dis 2010. DOI: 10.1016/j.numecd.2010.06.007.Sirot, V., Dumas, C., Desquilbet, L., Mariotti, F., Legrand, P., Catheline, D., et ...
cubic splines是data interpolation的方法。精髓就是相邻点点(knots 是曲线必经点点的意思)之间都是三次方程（cubic polynomial ）. restricted cubic splines比cubic splines特殊的地方就是要求点点两边外侧是直线（linear)，中间是cubic splines，而且要自己，一次，二次微分都连续（continuous）。a spline wit...
Sepsis is a life-threatening condition that significantly increases mortality in leukemia patients.1 Due to the immunosuppressed state of leukemia patients, they are particularly vulnerable to infe...
A spline is a drafting tool for drawing curves. In statistics, splines are a broad class of methods for transforming variables. I first introduce the concept via linear splines and work my way to restricted cubic splines which is what I (and many others) recommend. You should be aware that...
(16) str; str = 'Hello World!'; put str; end; enddata; run; quit; CALCULATING RESTRICTED CUBIC SPLINES USING A SAS MACRO A number of people have written SAS® macros that calculate the variables needed to perform a restricted cubic spline analysis, or that perform the analysis for a ...
Restricted cubic spline analysis of the functional form of the association between age (years) and number of male partners in the last 12 months and the unprotected anal intercourse in the final model, IPEC/Fiocruz, 2010–2012. Full size imageDiscussion...
Restricted cubic splines are just a transformation of an independent variable.Thus, they can be used not only in ordinary least squares regression, but also in logistic regression,survival analysis, and so on. The range of values of the independent variable is split up, with "knots"defining ...
Two types of models were applied—a linear and nonlinear model with restricted cubic splines—to assess the U-shaped association. Statistical significance (set at 0.05) for the nonlinearity was tested by comparing the spline and linear models. Among the participants, 701 were certified as needing ...
Pulse rate was classified as, < 60/min, 60–90/min (as reference), and ≥ 90/min according to the non-linear association with SCD captured by cubic spline analysis (Fig. 2). Figure 2 Restricted cubic spline curve for association (95% CI) of pulse rate with SCD events among...
Similar findings were also observed in the continuous analysis using restricted cubic splines with a reverse J-shaped association between BMI and the risk of all-cause mortality (Fig. 3). The nadir for all-cause mortality risk among patients with acute severe hypertension was estimated from model...