Jean Chretien
BULLET PROOF JESUS BURNING BUTTERFLIES BURNS & SONG BUTCHERS Butler Brothers BY LIGHT OF DESERT NIGHT BY THE GRACE OF GOD Byeol Kang C. Thomas Howell C.A.M C.M. Talkington CADDY HACK Cade Tropeano CADEJO BLANCO CAGEFIGHTER: WORLDS COLLIDE CAIN HILL Caitlin Cameron Cai...
A proof of concept is conducted by using the LoTToR on a phantom, i.e., a simulated 3D reconstruction from a low-tilt series of images, including that within a tilt range of ±15°. The method is validated by using both negative-staining (NS) and cryo-electron tomography (cryo-ET) ...
10, 11 To date, there is no efficient treatment for FA. Replenishment of frataxin either through epigenetic drugs, protein replacement, or gene therapy would be the optimal therapy for FA. Previously, we established a proof of concept for a gene therapy approach using adeno-associated virus (...
B. Cannon's group who tested, within the framework of our project, the action of SkQ1 on progeric Larsson's “mutator mice” with the D257A mutation in the proof-reading domain of mitochondrial DNA polymerase γ. Such a mutant polymerase can synthesize DNA but cannot recognize and repair ...
A proof-of-concept in medication development for alcohol use disorder Article 24 November 2020 References Allgaier C, Franke H, Sobottka H, Scheibler P . (2000): Acamprosate inhibits Ca2+ influx mediated by NMDA receptors and voltage-sensitive Ca2+ channels in cultured rat mesencephalic neuron...
For industrial bioproduction, Escherichia coli is one of the most widely used organisms due to economically viable cell growth, high cell density, ease of manipulation and often it is also used for proof of concept at laboratory scale [20, 21]. E. coli has also been used for recombinant spi...
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the two-level factor ‘WEEKDAY’ with values 0 and 1 indicating if the consultation date is a weekend day (Saturday, Sunday or public holiday) or a working weekday (Monday to Friday), respectively -we considered using day of the week as a factor on 7 levels, but this did not improve...
Despite the successful proof-of-concept demonstration of the half-cell battery with Si nanowire anode, solid strategies should be dedicated to enhance its performance (e.g., the use of higher, smaller diameter, and denser nanowire arrays). The fabrication technique presented in this study could ...