The present article tries to summarize the recent findings on mortalin's role in carcinogenesis and proposes it as a potential target for cancer therapy.Lu, WLuk, JMC分子诊断与治疗杂志
Mortalin: a potential target for cancer therapy 分子诊断与治疗杂志 21年700 月第 2卷第 4期 JMo anTeuy21,o. . lDi hrl00V12No4g,J ?l? 27 。还述 ? 伴。评 ? Motln: tnta agtfrcncrtrpyraiapoeilre o ae hea tLUWejg,onMLkni Jhnu (.eametfugr,h iesyoHogKn,ogKn,hn;.eatnfhrclg ...
Cutl1: A potential target for cancer therapy 来自 Semantic Scholar 喜欢 0 阅读量: 69 作者:KC Liu,BS Lin,M Zhao,KY Wang,XP Lan 摘要: Cutl1 and development. Activities of Cutl1are variable and thereby influences its DNA-binding. Cutl1 promotes cancer progression through its downstream ...
had a poorer prognosis. The researchers stated that more studies are needed to confirm RIOK1 as a target forcancer therapy, however. It would be important, for example, to understand the exact mechanism through which the enzyme supports cancer growth and metastasis. It is also essential that in...
Thyroid cancer is a heterogeneous disorder characterized by gene mutations that activate signaling pathways, and also by abnormalities in tumor suppressor genes and cell cycle proteins. Activation of the Akt / PKB signaling pathway appears to be an important event in thyroid tumorigenesis and, perhaps...
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc. Natl Acad. Sci. USA 94, 6658–6663 (1997). The paper reported a link between MYC and metabolism and identified LDHA as a potential target for cancer therapy. Article CAS PubMed PubMed Central Google Scholar...
Pathways upstream of TOR are frequently activated in cancer. This can be through increased activity of phosphatidylinositol-3-kinase–AKT or kinases that regulate TSC2, or through mutations that inactivate TSC proteins. The TOR pathway is also upregulated in many human cancers and oncogenic transforma...
xPC Target 快速原型控制 硬件在回路 实时仿真 肝癌组织Mortalin表达水平对术后复发的影响 肝细胞癌 表达 肝切除 复发 Mortalin文献信息 引文网络 相关学者/机构 期刊文献 文献信息 篇名 Mortalin:a potential target for cancer therapy 来源期刊 分子诊断与治疗杂志 学科 关键词 年,卷(期) 2010,(4) 所属...
of the phosphatase PTPN2 in tumour cells enhances interferon-γ-mediated effects on antigen presentation and growth suppression. This finding suggests that PTPN2 is a potential target for cancer immunotherapy and thatin vivogenetic screenings of tumour models could help identify other possible targets....
Vimentin in cancer and its potential as a molecular target for cancer therapy Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously expressed in normal mesenchymal cells and is known to mainta... A Satelli,S Li - 《Cellular & Molecular Life Sciences》 被...