Patients with neurogenic rosacea (NR) frequently demonstrate pronounced neurological manifestations, often unresponsive to conventional therapeutic approaches. A molecular-level understanding and diagnosis of this patient cohort could significantly guide clinical interventions. In this study, we amalgamated our se...
The optimal recommended dose is 2 mg/kg/cycle for IVIG therapy [58]. The average duration of treatment consisted of 24 months and an average of 15 cycles were administered for each patient [51]. In 2017 a large, multicenter, clinical trial was carried out to determine the effect of high...
Simultaneously O2 administration via a face mask was increased to 15 lt/min and intravenous fluid administration was increased. There was no improvement in the patient’s hemodynamic state and his blood pressure dropped further to 55/35 mmHg and the patient then became unresponsive. Fearing imminent...
The discomfort is often worse when the patient is supine (e.g., in bed) and may lessen when the limb is maintained in the dependent position. Typically, narcotic medications are required for analgesia. Those factors that are known to increase the risk of limb loss in patients with CLI are...
Resting EEG (rEEG) evaluates the brain while the patient is at rest or in other words not exposed to a repeated, standardized stimuli. In the critical care setting primarily, rEEG is used to detect seizures, a potentially reversible cause of DoC. It can further be used as a monitor for...
EEG monitoring of brain function in the comatose patient What is important Continuous EEG (c-EEG) is indicated for the man- agement of refractory status epilepticus. In this set- ting, when to use continuous versus intermittent EEG remains debated [11]. Most epileptic abnormalities can...
1a, c). Seizures experienced by patient 1 are partially responsive to medications and are currently controlled, while the seizures of patient 2 have been unresponsive or only partially responsive to multiple medications (Supplementary Table 1). Both patients had early developmental delay, and meet ...
From this has emerged the concept of personalized medicine (PM), which is a medical scheme that combines study of genetic, environmental and clinical diagnostic testing, including biomarkers, to individualized patient care. In this perspective, we used subgroups of specific ALS-linked gene mutations ...
Patient and disease characteristics were well balanced between groups (table 1). The median time from induction therapy randomisation to CVD randomisation was 5·7 months (IQR 4·7–6·9) in the CVD group versus 5·8 months (4·6–6·7) in the no CVD group. Table 1. Baseline ...
The test dose should be repeated if the patient is moved in a manner that may have displaced the catheter. Epinephrine, if contained in the test dose (10–15 mcg have been suggested), may serve as a warning of unintentional intravascular injection. If injected into a blood vessel, this ...