The prevention of malaria is a multi-step process that usually begins at the individual and household level, and progresses up to the government and medical facility provider level. At theindividual level, the most effective prevention method is vector control. Like most vector-borne diseases, mala...
Santamaria R, Rizztto L, Bromley M et al (2011) Systems biology of infectious diseases: a focus on fungal infections. Immunobiology 216:1212–1227Rodrigo, Santamar铆aLisa, RizzettoMichael, BromleyTeresa, ZelanteWanseon, LeeDuccio, CavalieriLuigina, RomaniBrian, MillerIvo, GutManuel, Santos...
Mood and anxiety disorders are frequent in the elderly and increase the risk of frailty. This study aimed to identify novel biomarkers of major depressive
Indeed, scRNA-seq can provide abundant transcriptomic data to study molecular events and cell heterogeneity at the single-cell level. However, due to hereditary deficiency, high-expression genes in the library are sequenced more frequently, and rare genes can be easily ignored. Therefore, it is ch...
Furthermore, antimicrobials were estimated in food animal use at a global level of more than 130,000 tons in 2013 and 200,235 tons by 2030. Indeed, the United Nations (UN) reported that the increase in AMR was partly due to antimicrobial abuse in animals [6]. Meanwhile, resistant gene ...
This finding suggests that, at least for any tinnitus, not all the variability is explained by different definitions, and other factors might explain the prevalence of any tinnitus better at the population level. Concomitantly, our findings suggest that data on tinnitus among children or adolescents...
(μg/ml) of 1.6C7/28D9 binding to MERS-Sectomutants containing single amino acid substitutions in the core epitope region are indicated on the left. Anti-MERS-S1 control antibody 7.7G6 was used to control the expression level of all mutants. n.b., no binding. The average fromn =...
While the overall degree of infection in hACE2KI-NSG mice was considerably more severe than that in hCD147KI-NSG mice, we observed a significant body weight drop, higher SARS-CoV-2 RNA level, and detected multiple SARS-CoV-2 infected cells in the lungs of both hCD147KI-NSG and hACE...
exposed the cells to 0.06 µg/ml micafungin (4xMIC) for 1 h, and assessed survival by CFU counts. Consistent with studies of bacterial persisters19,21,23,44, we found that a high level of tolerance can be induced as early as after 15 min of incubation in spent RPMI + ...
ELISA was used to assess the induction level of IFN-β in A549 cells (B) and H460 cells (D) after treatment with N protein and PIC. (E) WB was used to verify the expression level of SARS-CoV-2 encoded proteins in A549 and H460 cells transfected with N, S, M and E expression ...