The ArlS-ArlR two-component system is involved in the expression of virulence genes such as spa. Presence of an arlRS deletion decreased the effect of DNA supercoiling modulators on spa expression, suggesting that active Arl proteins are necessary for the full effect of DNA gyrase inhibitors ...
in starved escherichia coli. a novel dna-binding protein with regulatory and protective roles references M Almirón,AJ Link,D Furlong,... 被引量: 0发表: 2017年站内活动 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们...
base is added or deleted from the string of bases, which may result in production of a completely dysfunctional protein[8]. There are many ways that errors can be made in DNA replication or in the processes that follow. When genes are expressed they are turned on and they make a protein...
We isolated a cDNA encoding a DNA-binding protein, SPF1, of sweet potato that binds to the SP8a (ACTGTGTA) and SP8b (TACTATT) sequences present in the 5′ upstream regions of three different genes coding for sporamin and β-amylase of tuberous roots. SPF1 comprises 549 amino acids ...
DNA filtering parameter of 25% was used to ensure the inclusion of oocytes, because these are known to have more mitochondria than somatic cells22,23. In addition, mitochondrial-dependent apoptosis is involved in follicular atresia24and thus a lower filtering threshold may result in loss of ...
when they come into secondary contact31(Fig.1c, d), evidence suggests introgression is asymmetric32. Due to the simple structure of the vocal phenotype that is divergent between the two species and the extent of introgression between them32, this system provides the opportunity for a genome-...
Transcriptome sequencing showed that adenosine-to-inosine (A-to-I) RNA editing was responsible for 80% of the editing events in the myocardium. Failing human hearts were characterized by reduced RNA editing. This was primarily attributable to Alu elements in introns of protein-coding genes. In ...
We report that the main MIEF1 translational product is not the canonical 463 amino acid MiD51 protein but the small 70 amino acid alternative MiD51 protein (altMiD51). These results demonstrate the inadequacy of the single CDS concept and provide a strong argument for incorporating altORFs and...
The task of protein sequence design is central to nearly all rational protein engineering problems, and enormous effort has gone into the development of energy functions to guide design. Here, we investigate the capability of a deep neural network model
Replication of abacterial chromosomestarts at a specific point, theorigin of replication, which encompasses 245 base pairs of DNA that contain three 13bp repeats and four 9bp repeats. The DnaA protein binds first to the three high affinity DnaA boxes. Only then can the lower affinity DnaA ...