Infectious diseases are among the leading causes of mortality worldwide. A new coronavirus named severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) was identified in Wuhan, China in 2019, and the World Health Organization (WHO) declared its ou
Fig. 1. Diagram of the implementation process. 2. Background 2.1. COVID-19 related research Detecting COVID-19 with deep learning techniques is a trending topic and has attracted extensive attention recently. Promising results using advanced CNNs have been published and continue to emerge in this...
Fig. 8.1. Diagram of working steps of lab-on-a-chip (LOC) sensing devices. LOC devices and their associated microsystems and complementary technologies (μTAS, bio-MEMs, nanoelectromechanical systems [NEMS], microfluidics, etc.) developed from multidisciplinary fields, including chemistry, biology, ...
2,3,4,5. Mechanistic models, grounded in the known governing laws and physical principles of disease transmission, have been widely used to investigate various infectious diseases, including respiratory infections6,7,8, sexually transmitted diseases...
The schematic diagram of the experimental design is shown in Fig.1A. Female BRGSF mice, 8–10 weeks, were purchased from Cyagen Biosciences (Suzhou, Jiangsu, China) and housed under specified pathogen-free conditions, with 12-h light/darkness cycles, at the animal facility of South China Agric...
Transfer learning (TL) with convolutional neural networks aims to improve performances on a new task by leveraging the knowledge of similar tasks learned in advance. It has made a major contribution to medical image analysis as it overcomes the data scar
Summary of the process in a flow diagram Full size image The historical development of immunohistochemistry and automation Immunohistochemical staining is derived from immunofluorescence, and dates back to 1941, when Coons and colleagues demonstrated that tissues stained with fluorescein-conjugated antibodies ...
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a myriad of studies in animal models and also some clinical trials have evinced the sa
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective against inflammation to treat lethal COVID-19 are
Fig. 1: Participant flow diagram for the phase 2a LM11A-31 clinical trial. Examples of major protocol violations included failure to meet inclusion or exclusion criteria (data changed or violation was not detected before dosing), use of prohibited medication that began during the treatment period...