coronavirus disease 2019; HIV, human immunodeficiency virus; PBI, primary bacterial infectious disease; SD, sleep disorder; AD, Alzheimer’s disease; IS, ischaemic stroke; KD, Kawasaki disease; IBD, inflammatory bowel disease; T2D, type II diabetes. GNPS and and microbeMASST logos reproduced under...
Sendai virus (SeV) is an enveloped negative-strand RNA virus, and it mainly infects mice and rats, causing acute respiratory diseases resembling the human parainfluenza infection [135]. It was shown that SeV could induce cell apoptosis via activation of Caspase-8 and Caspase-3 [135]. The MV...
There are soils that even if there is the pathogen the disease does not occur, the mechanisms of these disease-suppressive are still being investigated. In this way, Mendes et al.,52 analyzed the microbiome of a soil suppressive to the fungal pathogen Rhizoctonia solani that causes damping off...
COVID-19 is a highly spreadable viral infection, reported first in Wuhan, China in December 2019 which spreads worldwide later. The pathogen of this diseas
Kampe AJ, Costantini A, Makitie RE, Jantti N, Valta H, Mayranpaa M, Kroger H, Pekkinen M, Taylan F, Jiao H, Makitie O (2017) PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants. Osteoporos Int 28(10):3023–3032. https://doi.org/10....
Chronic obstructive pulmonary disease CT: Culture threshold DNA: Deoxyribonucleic acid GEq: Genome equivalent HAP: Hospital-acquired pneumonia ICU: Intensive care unit mNGS: metagenomics Next Generation Sequencing MT: Metagenomic threshold PCR: Polymerase Chain Reaction RRT: Renal replacement th...
Pancreatic cancer (PC) is reported to be the third most common cause of cancer-related deaths in both sexes in the USA, with a very low 5-year survival rate of 12%, because most patients are identified in the late stages of disease [1]. It is estimated that there will be 64,050 ne...
Our study confirmed that CTA1-DD-adjuvanted H3N2 split vaccine activated IFN-γ secretion causing a predominant Th-1-type response. Collectively, the enhanced protection offered by the CTA1-DD-adjuvanted H3N2 split vaccine could be due to the effect of higher levels of serum IgG and IgA, the...
The importance of understanding the differences between mechanisms causing aMCI versus those leading to dementia is significant. It is one of the most challenging aspects in the research field of AD, because the pathophysiological process of AD in elders has begun in many years before the diagnosis...
. As a case study, a large-scale microbe-disease relation network analysis was performed to provide valuable information on whether a set of specific microbes are common or exclusive to a given disease or not. Since the proposed method provides a systematic way of extracting the microbe-disease...