Switching between antiparallel and parallel quadruplex structures oftelomeric DNA under the control of intracellular Na + and K + has been implicated in the pairing of chromosomes during meiosis. Using Raman spectroscopy, we have determined the dependence of the interquadruplex equilibrium of the ...
One germ cell is selected to become the oocyte and enters meiosis, while the others differentiate into nurse cells that provide support for the oocyte. At the midpoint in the germarium, each cyst becomes encapsulated by a layer of epithelial follicle cells produced by the follicle stem cells ...
The mosaic nature of the oat genome may be associated with the apparent lack of an orthologue of TaZIP4-B2 (located within the Ph1 locus), which in bread wheat stabilizes the genome structure during meiosis and suppresses crossovers between homoeologues22,23,24 (Extended Data Fig. 5b and ...
The diagram in (d) shows the rearrangement of the domains of the protein during this process (MACPF, the shared domain of the complement membrane attack complex (MAC) and perforin, which forms the core of this membrane ‘hole punch’; CH1 and CH2, α-helices that unwind to form hairpins...
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6A) as the proof-of-concept target. Fig. 6 In vitro validation of the interaction between RNF8 and YBX1. A The intersection of RNF8 interactome by LC–MS and potential RNF8-interacting proteins acquired using five online tools. B Schematic diagram of Co-IP. C HEK-293T cells were ...
The diagram shows paired homologous chromosomes. Genetics The genetic disorder at chromosome number 21 probably resulted from: 1. crossing-over during mitosis 2. failure to separate two chromosome pairs during meiosis 3. the crossing of two different species 4. organisms reproducing asexually ---...
We conclude that this region represents the pseudoautosomal region (PAR), where both sex chromosomes still pair in female meiosis and crossing over occurs at a normal rate. The remaining region of the sex chromosomes contains 297 genes, which are also present on Z and W but show some sequence...
of meiotic prophase I.dSchematic diagram of SC formation in meiotic prophase I. From the leptonema to the pachynema, the two lateral elements with a central element are assembled into SC with meiosis-specific proteins, including SYCP1 and SYCP3. In the diplonema stage, SC disassembly, ...
Moreover, murine and human ES cells differentiated into germ-line cells, underwent meiosis and produced sperm or oocytes, respectively [5, 6]. Regarding the regulation of germ cell development, it was found that DAZL (deleted in azoospermia-like, DAZL) gene expression played a primary role in...