The present invention provides a method of producing a carboxylic acid having 1 to 3 carbon atoms, 2,3-butane diol and / or acetoin, is reacted with the carboxylic acid having 1 to 3 carbon atoms to a method which is characterized in that.クリストフ リューディンガー...
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Drug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps. Here, we
(R3)- wherein R3 represents a hydrogen atom, a phenyl or an alkyl group of 1-4 carbon atoms, which process comprises reacting an azetidine of the formula II: <CHEM> wherein R1 has the meanings defined above, and X represents a hydrogen atom, a carboxyl or a group, with an alkali ...
Carbon-carbon coupling between olefinic C atoms on a cluster as a Lewis acid-base reaction 来自 ACS 喜欢 0 阅读量: 33 作者:D Heineke,H Vahrenkamp 摘要: A study was carried out on the conformation of the dioxane ring and orientation of the substituents in 5-aryl-5-nitro-2-R-1,3-...
Among them, SCFAs (carboxylic acids with an aliphatic chain length of up to six carbon atoms (Silva et al., 2020)) have been widely applied in food, chemical, biochemical, textile, cosmetic or pharmaceutical industries (Panda et al., 2019). The global market for lipids was estimated at ...
Selectivity for MAO-B increases with increase in number of carbon atoms between two oxygen atoms Residue Y398, I199, Y435 interacted via pi-pi bond Parambi et al., 2019 22 MAO-A0.047 μMMAO-B0.020 μM Methylenedioxy moiety at ring B and Cl at ring A improv...
Aromatic acids with an odd number of side-chain carbon atoms (3-phenylpropionate, 5-phenylvalerate, 7-phenylheptanoate) gave greater apparent molar growth yields than those with an even number of side-chain carbon atoms (4-phenylbutyrate, 6-phenylhexanoate, 8-phenyloctanoate). HPLC analysis ...
Calcimycin is synthesized by modular CalA1, A2, A5, and A412, in which the domain organization matches well with the carbon backbone of the pyrrole 2-carboxylic acid-primed polyketide chain (Supplementary Fig. 2a). This chain reacts with 3-hydroxyanthranilic acid (3-HAA) in a hitherto ...
In the present invention, the process for activating by use of a phosphonium salt, (a) the carboxyl group of a carboxylic acid represented by the formula, R1COOH (I) wherein R1is an alkyl group having 1-30 carbon atoms, preferably 1-18 carbon atoms, a halogen-substituted alkyl group hav...