bromoform, and chloroform have been shown to be potent inhibitors of CH4formation in both in vitro and in vivo studies8,9,10. The anti-methanogenic activity is usually related to the number of halogens on the molecule with iodine-containing compounds being the most efficient followed by bromina...
Rhabdomyolysis is a potentially life-threatening syndrome resulting from the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. The most common causes are crush injury, overexertion, alcohol abuse and certain medicines and toxic substances. Several inherited genetic ...
In the first part of the small intestine, called the duodenum, enzymes from the pancreas are added. These enzymes complete the chemical breakdown of the food. The digestion of fat is aided by bile, which is made in the liver and stored in the gall bladder. The small intestine of an ...
Aging is among the most important risk factors for morbidity and mortality. To contribute toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data from multiple studies. Here, we show that transcript length alone explains m
This is in sharp contrast to the increases in uptake of 125I-labeled human serum albumin after anti-Fas treatments that were interpreted to be due to an expanded extracellular fluid volume from breakdown of hepatic endothelial cells [47]. Anti-Fas treatment eventually causes gross injury with ...
Matrix metalloproteinase 9 (MMP-9), also known as gelatinase B with a molecular weight of 92 kDa, belongs to the MMP family of 24 zinc-dependent endopeptidases that is involved in the breakdown of extracellular matrix. The regulation of the MMP occurs at gene transcription, protein translation...
Cancer rates are set to increase at an alarming rate, from 10 million new cases globally in 2000 to 15 million in 2020. Regarding the pharmacological treatment of cancer, we currently are in the interphase of two treatment eras. The so-called pregenomic
There is a phenomenon in medicine called rapidly destructive osteoarthritis. This is an osteoarthritis breakdown that suddenly, without a seemingly good explanation, accelerates joint osteoarthritis, or in the case of this article, a super accelerated hip osteoarthritis. In our clinic...
embryos of the Blechschmidt collection. The latter embryo did not suffer from venous congestion. The configuration of the atrial chambers and their topographic relation with the pulmonary vein are similar to those in the previous stage61,62,63. The breakdown of the dorsal portion of the primary ...
As previously described in this system of glutamate toxicity in HT-22 cells,32,33 the oxidative cell death is associated with a breakdown of mitochondrial membrane potential (MMP). Measurement of MMP revealed a reduction of mitochondrial Cell Death and Disease Inhibition of HIF-PHDs prevents ...