of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P0506...
Recovery A known concentration of the target protein was added to 5 samples which were diluted to different multiples, and a recovery experiment was performed to obtain a recovery range and an average recovery rate. 相关文档我的购物车(0) 结算 关于...
Synthetic beta-amyloid AB1-42was monomerized by HFIP (hexafluoro-2-propanol) treatment and dried. One vial contains 50 µg monomeric AB peptide that can be used to form solutions of unaggregated AB monomers, aggregated AB oligomers, AB fibrils and AB protein complexes according to published pr...
The amyloid-β (Aβ) peptides that form the amyloid fibrils associated with Alzheimer’s disease are generated by sequential proteolysis of the amyloid precursor protein by β- and γ-secretase. The two predominant Aβ peptides, Aβ40 and Aβ42, differ by two amino acids, are soluble as ...
synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A antibody format rabbit; polyclonal; serum; lyophilized quantity 100 µl - for reconstit...
and is said to be cleaved out of the precursor protein APP by the action of β- or γ-secretase.In addition, the presence of numerous variant A β molecules has been demonstrated in the culture fluid of mouse neuroblastoma cells transfected with cDNA coding human amyloid precursor protein (APP...
Besides of the patho- logical aggregation of tau protein7 the other major neuropathological hallmark of AD is the accumulation of extracellular neurotoxic amyloid-β (Aβ ) peptides have so far largely been ineffective resulting in an sinuacbhilaistyAtβo 1t–r4e2aint tthheepbrroafion...
抗体名:beta Amyloid(1-42); beta Amyloid 1-42; beta-Amyloid 1-42; Amyloid 1-42; beta-Amyloid 42; A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid...
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The DNA construct was inserted into pAED4 vector (Doering and Matsudaira, 1996) and the protein expression was carried out in E. coli BL21 (DE3) pLysS strain (Novagen, Inc., Madison, WI), using 1 mM IPTG for induction. The peptide accumulated in the inclusion bodies of the bacterial ...