( 1999 ) Interaction between A beta (1–42) and A beta (1–40) in Alzheimer's beta-amyloid fibril formation in vitro . Biochemistry 38 , 15514 – 15521 .Hasegawa K., Yamaguchi I., Omata S., Gejyo F. and Naiki H. (1999) Interaction between A beta (1-42) and A beta (1-40)...
(2002) Elevated levels of Abeta1-40 and Abeta1-42 do not alter the binding sites of nicotinic receptor subtypes in the brain of APPswe and PS1 ... Amelia Marutle and Christina Unger and Ewa Hellström-Lindahl and Jun Wang and Jukka Puoliväli and Heikki Tanila and Agneta Nordberg ...
Background: Abeta-amyloid 1-42 (abeta) and tau-protein (t-tau) in cerebrospinal fluid (CSF) have been identified as powerful biomarkers for Alzheimer's disease (AD). Whereas t-tau seems to reflect the intensity of the neurodegenerative process, abeta is believed to diminish cognitive plastic...
An UHPLC-MS/MS method for simultaneous quantification of human amyloid beta peptides Aβ1-38, Aβ1-40 and Aβ1-42 in cerebrospinal fluid using micro-elutio... Amyloid beta (Aβ) peptides in cerebrospinal fluid are extensively estimated for identification of Alzheimer's disease (AD) as ...
Amyloid-beta 1-42 and amyloid-beta 1-40 induce tau phosphorylation in human neutonsCaroline. Bélair
A beta 1-42 was independently associated with PCoI (odds ratio 0.973; 95% confidence interval: 0.950-0.996; p=0.024). Factors associated with plasma A beta 140 were age, smoking and diabetes mellitus. After exclusion of hemorrhagic strokes, the results remained unchanged, but blood samples ...
BACKGROUND Plasma biomarkers that reflect specific amyloid beta (Abeta) proteoforms are essential to monitor treatment effects of Alzheimer's disease (AD) therapies. Our aim was to develop and validate ready-to-use Simoa 'Amyblood' assays that measure full length Abeta1-42 and Abeta1-40 and...
beta-Amyloidbeta-Secretasegamma-SecretaseBackground: Amyloid-beta (A beta) peptides are a family of proteins that are considered to be a principal aspect of Alzheimer's disease (AD), the most common cause of senile dementia affecting elderly individuals. These peptides result from the proteolytic...
A beta(1-42) peptides in films has been investigated with IR and vibrational circular dichroism (VCD) spectroscopy. From IR spectra, it is shown that the prepared films of A beta(1-40) and A beta(1-42) mainly comprise the beta-sheet conformation that is characteristic of aggregated and ...
The anxiogenic effects of Abeta (1- 40) and Abeta (1-42) in the dorsal raphe nucleus in male ratsdoi:10.1016/j.jalz.2009.04.459ShervinGholizadehandTookaAavaniandFereshtehMotamediSDOSAlzheimers & Dementia