The invention further relates to methods for converting cholic acid (CA) and/or chenodeoxycholic acid (CDCA) into ursocholic acid (UCA) and/or ursodeoxycholic acid (UDCA) respectively, and more specifically methods for converting 7-oxo-deoxycholic acid (7-oxo-DCA) and/or 7-oxo-lithocholic acid...
3-氧-2-苯基丁酸,英文名为3-oxo-2-phenylbutanoic acid,CAS号为4433-88-9,海关编码2918300090;3-氧-2-苯基丁酸酯类物质,是指3-氧-2-苯基丁酸与各种醇反应生成的酯类物质,英文名为3-oxo-2-phenylbutanoic acid esters,海关编...
[0008]综上所述,通过酶法催化7‑羰基石胆酸(7‑oxo‑LCA)的不对称还原反应合成熊去氧胆酸,具有立体选择性高和环境友好等优势,已有诸多相关报道,并取得了一定进展。但是,现有技术的7β‑羟基甾体脱氢酶依然存在许多不足之处,例如我们通过实验验证发现目前公开报道的许多7β‑羟基甾体脱氢酶的催化活性实际上...
Structure of 1AHH contains ligand NAD+ at resolution 2.30 Å, while both 1FMC and 1AHI have the ligands NADH and 7-oxo-GCDCA at resolution 1.80 Å and 2.30 Å, respectively. In spite of the low sequence identity (only 15–30%), SDRs generally display the well-conserved ...
CACTVS Substructure Key Fingerprint:AAADcfB//gBgAAAAAAAAAAAAAAAAASJAAAA0aIEAAAAAAAAAAAAAHgAQCAAADHzxgAcDCALABoAgAAAAJDAAAAEAAAAAAIAIAAATEAIAwAAnQAAHEAAXAAHwcA8KAAAAAAAAAAACgAAUCACgAAAAAAAAAA== 其他 应用双氢链霉素(多以硫酸双氢链霉素形式保存)是一种高效β-内酰胺类抗生素,具有杀菌活性强、毒性低、适应...
(5) 3alpha-Hydroxy-7-oxo-5beta-cholic acid(7K-LCA) CAS #:4651-67-6 (6) Ursodeoxycholic Acid(EP9/USP/IP GRADE WITH GMP) CAS #:128-13-2 (7)Tauroursodeoxycholic acid EP9 CAS #:14605-22-2 (8)Obeticholic Acid (OBCA) 98%/99% CAS #:459789-99-2 ...
Ursodeoxycholic acid-d4(UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No.15121) by GC- or LC-MS. UDCA is a secondary bile acid formedviaepimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in...
(5) 3alpha-Hydroxy-7-oxo-5beta-cholic acid(7K-LCA) CAS #:4651-67-6 (6) Ursodeoxycholic Acid(EP9/USP/IP GRADE WITH GMP) CAS #:128-13-2 (7)Tauroursodeoxycholic acid EP9 CAS #:14605-22-2 (8)Obeticholic Acid (OBCA) 98%/99% CAS ...
4,5-Dinitro-9-oxofluorene-2,7-disulfonic acid bis(diethylamide) (21b) 4,5-Dinitro-9-oxofluorene-2,7-disulfonyl dichloride (18) (2.33 g, 5.0 mmol) was added to a stirred solution of diethylamine (5 cm3) in N,N-dimethylformamide (DMF, 15 cm3). The reaction mixture was stirred for...
To our knowledge, however, the chemical synthesis of 1a and 1b, which have a Δ4-3-oxo-7α-hydroxy structure in the steroid nucleus and the iso-octane (cholestane) side chain at the C-17 position, has not yet been reported. During the course of our studies on bile acid metabolism ...