Dietary variables associated with DNA N7- methylguanine levels and O6-alkylguanine DNA-alkyltransferase activity in hu- man colorectal mucosa. Carcinogenesis. 2009;30:615-620.Billson, H. A., Harrison, K. L., Lees, N. P., Hall, C. N., Margison, G. P. & Povey, A. C. (2009). ...
N7-methylguanineO6-methylguanineN-nitrosarnineMethyl-DNA adducts are induced by a number of lifestyle, environmental and occupational carcinogens, however knowledge about their kinetics is scarce. Here, N7-methylguanine (N7-MeGua) and O6-methylguanine (O6-MeGua) levels were determined in the DNA...
Method : In this study, we measured cigarette smoke exposure markers, such as urinary cotinine, PAH exposure markers, such as urinary 1-hydroxypyrene (1-OHP), 2-naphthol (2-NP) and 1-naphthol (1-NP), as well as a methylating chemical exposure marker, 7-methylguanine (7-MeG). The ...
7-methylguaninem 7Ino 7-methylinosine7-methylinosinem 7Hx 7-methylhypoxanthine7-methylhypoxanthineACG acycloguanosine or 9-(2-hydroxyethoxymethyl)guanine... E Kulikowska,A Bzowska,J Wierzchowski,... - 《Biochimica Et Biophysica Acta》 被引量: 119发表: 1986年 Initial levels of azoxymethane-ind...
Synthesis and chemical properties of monomers and polymers containing 7-methylguanine and an investigation of their substrate or template properties for bacterial deoxyribonucleic acid or ribonucleic acid polymerases Biochemistry, 9 (1970), pp. 4141-4153 CrossrefGoogle Scholar 15 P. Reichard Ribonucleotide...
, 7-methylguanine and 7-methyladenine, 2-F-adenine, 2-aminoadenine, 8-azaguanine and 8-azaadenine, 7-deazaguanine and 7-deazaadenine and 3-deazaguanine and 3-deazaadenine. In certain embodiments, oligonucleotide inhibitors targeting miR-92 comprise one or more BSN modifications (i.e., LNAs...
O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo. Proc Natl Acad Sci USA 2009; 106: 576–581. 55. Glassner BJ, Weeda G, Allan JM, Broekhof JL, Carls NH, Donker I et al. DNA repair methyltransferase (Mgmt) knockout mice are ...
Cross-linking of DNA induced by chloroethylnitrosourea is presented by O6-methylguanine-DNA methyltransferase. Nucleic Acids Res. 11, 7743–7758 (1983). 23 Radwanska, A., Litwin, M., Nowak, D., Baczynska, D., Wegrowski, Y., Maquart, F. X. et al. Overexpression of lumican affects ...
Promoter status of O6-methylguanine-DNA methyltransferase (MGMT) has been widely established as a clinically relevant factor in glioblastoma (GBM) patients... YH Zhao,ZF Wang,CJ Cao,... - 《Frontiers in Neurology》 被引量: 7发表: 2018年 加载更多来源...
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase Redox Biol., 13 (2017), pp. 655-664 Google Scholar [52] S. Kiritoshi, T. Nishikawa, K. Sonoda, D. Kukidome, T. Senokuchi, T...