The present invention relates to novel biocatalytic processes involving whole cell reduction of dehydrocholic acid (DHCA) compounds, novel 7尾-hydroxysteroid dehydrogenase variants, sequences encoding these enzyme variants, methods for producing enzyme variants, and The present invention also relates to ...
The invention relates to novel biocatalytic processes comprising the whole cell reduction of dehydrocholic acid (DHCA) compounds, novel 7尾-hydroxy steroid dehydrogenase mutants, the sequences coding for these enzyme mutants, methods for producing the enzyme mutants and use thereof in enzymatic ...
The present invention relates to a novel biocatalytic process comprising whole cell reduction of dehydrocholic acid (DHCA) compound, a novel 7-hydroxysteroid dehydrogenase mutant, a sequence encoding these enzyme mutants, a method for producing an enzyme mutant, The present invention also relates to ...
The enzyme shows the following property profile in comparison with the 7β-HSDH with SEQ ID NO:2: (a) an increased specific activity (Vmax [U/mg]) for NADPH in the enzymatic reduction of dehydrocholic acid (DHCA) with NADPH as cofactor.WERNER HUMMEL...