Pilot study of a novel nanobody 68Ga-NODAGA-SNA006 for instant PET imaging of CD8+ T cells. Eur J Nucl Med Mol Imaging. 2022;49(13):4394–405. Article CAS PubMed Google Scholar Ge S, Wang C, You X, He H, Zhang B, Jia T, et al. Imaging and monitoring HER2 expression in ...
Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma. J Nucl Med. 2016;57:27–33. https://doi.org/10.2967/jnumed.115.162024. Article CAS PubMed Google Scholar Li T, Qi S, Unger M, Hou YN, Deng QW, Liu J, et al. Immuno-targeting ...
(nanobody)”或VHH(Variable Domain of Heavy Chain of Heavy Chain Antibody),它们 可互换使用。纳米抗体具有本领域技术人员通常理解的含义,其是指由单个单体可变抗体 结构域(例如单个重链可变区)所组成的抗体片段,通常来源于重链抗体(例如骆驼科动物 抗体或鲨鱼抗体)的可变区。典型地,纳米抗体由4个构架区和3个互...
2016. Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma. J Nucl Med 57:27-33. https://doi.org/10.2967/jnumed .115.162024.
. The 68Ga–DOTA Z HER2:2991 probe showed a high affinity for HER2 breast cancer cells, with tumor accumulation correlating with HER2 expression. Biodistribution studies showed high tumor accumulation in HER2 positive BT474 breast with 31±2.1% ID at 1 h post-injection. Clearance from blood ...
2016. Phase I study of 68Ga-HER2-nanobody for PET/CT assessment of HER2 expression in breast carcinoma. J Nucl Med 57:27-33. https://doi.org/10.2967/jnumed .115.162024.