W. (1992) Human 6-pyruvoyl-tetrahydropterin synthase : cDNA cloning and heterologous expression of the recombinant enzyme, Biochem. Bio- phys. Res. Commun. 189, 1437-1443.THÖNY B ET AL: " Human 6-pyruvoyltetrahydropterin synthase: cDNA cloning and heterologous expression of the recombinant ...
6-pyruvoyl tetrahydropterin synthase deficient form 6-丙酮酰四氢蝶呤合成酶缺乏型文献(pubmed) 赞助商链接以下为句子列表:英文: Gene Cloning of Trehalose-6-phosphotate Synthase from Saccharomyces Cerevisiae中文: 酵母海藻糖磷酸合成酶基因的PCR扩增及其产物克隆 ...
6-丙酮酰四氢蝶呤合酶(PTPS)缺乏症的英文名字是6-Pyruvoyl-Tetrahydropterin Synthase (PTPS) Deficiency。基因解码表明:佳学基因通过基因解码发现:6-丙酮酰四氢蝶呤合酶(PTPS)缺乏症是由PTPS基因的突变引起的。PTPS基因编码了6-丙酮酰四氢蝶呤合酶酶,该酶在体内合成四氢生物蝶呤(BH4)的过程中起关键作用。
The putative gene (ygcM) of Escherichia coli was verified in vitro to encode the ortholog of 6-pyruvoyltetrahydropterin synthase (PTPS). Unexpectedly, the enzyme was found to convert sepiapterin to 7,8-dihydropterin without any cofactors. The enzymatic product 7,8-dihydropterin was identified by...
1.Objective To study the effects of sodium arsenite on the mRNA expression of GTP cyclohydrolase (GTPCH) and 6-pyruvoyl-tetrahydropterin synthase (PTPS) in Chang liver cells.目的研究亚砷酸钠(NaAsO2)对Chang肝细胞鸟苷三磷酸环化水解酶I型(GTPCH)及6-丙酮酰四氢蝶呤合成酶(PTPS)的mRNA表达水平的...
(sj2has been identified to encode the enzyme, and its cDNA has been cloned recently. The cDNA encoding the 19.3 kDa subunit of the 6-pyruvoyl tetrahydropterin synthase was expressed as fusion proteins inE. coli.The recombinant protein was shown to be active and purified from theE. colicrude ...
BH4 is formed de novo from GTP via a sequence of three enzymatic steps carried out by GTP cyclohydrolase I, 6-pyruvoyltetrahydropterin synthase and ... ER Werner - 《Biochemical Journal》 被引量: 259发表: 2011年 Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1...
limicola needs an additional enzyme for l -erythro-BH4 synthesis to yield its glycoside. The catalytic activity of Chlorobium SRs also supports the previously proposed mechanism of two consecutive reductions of C1' carbonyl group of 6-pyruvoyltetrahydropterin via isomerization reaction. 展开 ...
limicola needs an additional enzyme for L-erythro-BH4 synthesis to yield its glycoside. The catalytic activity of Chlorobium SRs also supports the previously proposed mechanism of two consecutive reductions of C1' carbonyl group of 6-pyruvoyltetrahydropterin via isomerization reaction....
Steinerstauch, P, Wermuth, B, Leimbacher, W, Curtius, H-Ch (1989) Human liver 6-pyruvoyl tetrahydropterin reductase is biochemically and immunologically indistinguishable from aldose reductase. Biochem. Biophys. Res. Commum. 164: pp. 1130-1136...