5.中国医师协会结直肠肿瘤专业委员会,等. 结直肠癌靶向治疗中国专家共识. 中华结直肠疾病电子杂志,2022,11(5):353-360. 6.Arnold D, et al. Prognostic and predictive value of primary tumour side in patients with RAS wild-...
参考文献 1. Kim R, An M, Lee H, Mehta A, Heo YJ, Kim K-M, et al. Early Tumor-Immune Microenvironmental Remodeling and Response to First-Line Fluoropyrimidine and Platinum Chemotherapy in Advanced Gastric Cancer. Cancer Discov. 2022;12:984–1001.2. Tang X, Li M, Wu X, Guo T, Zhan...
4、Che J, Pan L,Yang X, et al. Thymidine phosphorylase expression and prognosis in colorectalcancer treated with 5‑fluorouracil‑based chemotherapy: A meta‑analysis.Molecular and clinical oncology. 2017 Dec 1;7(6):943-52. 5、Sakowicz-...
4. Macaire, P., et al.,Therapeutic drug monitoring as a tool to optimize 5-FU-based chemotherapy in gastrointestinal cancer patients older than 75 years.Eur J Cancer, 2019.111: p. 116-125.
Reports also indicate several other miRNAs, which in various types of cancer may regulate the level of protein encoded byTYMSand thus affect the sensitivity of cancer cells to 5FU chemotherapy, including miRNA such as miR-140-3p (Wan et al.2021), miR-197-3p (Sun et al.2015), miR-203a...
Neuroendocrine tumorChemotherapyStreptozotocin5-FUPurpose The standard of care treatment for patients with advanced pancreatic neuroendocrine tumors (pNET) is a combination of streptozotocin and 5-FU. Although widely used, little is known about the best long-term strategy with these substan...
(52.5 mg/kg,每周给药2次,连续2周,停1周)、每日节拍化疗 (daily metronomic chemotherapy,MET-qd)组 (10 mg/kg,每天1次,连续6周)、隔日节拍化 疗(every other day metronomic chemotherapy,MET-qod)组(20 mg/kg,隔日1次,连续6周)和每周2次节拍化疗(twice-weekly metronomic chemotherapy,MET-biw)组(30 ...
6.Morton D, et al. Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial. J Clin Oncol. 2023 ;41(8):1541-1552. 7.中国南方肿瘤临床研究协会结直肠癌专业委员会....
3.Deborah Schrag, et al. PROSPECT: A randomized phase III trial of neoadjuvant chemoradiation versus neoadjuvant FOLFOX chemotherapy with selective use of chemoradiation, followed by total mesorectal excision (TME) for treatme...
Keil F, Hartl M, Altorjai G.et al. Docetaxel, cisplatin and 5-FU compared with docetaxel, cisplatin and cetuximab as induction chemotherapy in advanced squamous cell carcinoma of the head and neck: Results of a random...