5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。 规格价格库存数量 10 mg¥ 256现货 25 mg¥ 414现货 50 mg¥ 697现货 100 mg¥ 1,247现货 ...
5′-methylthioadenosine (MTA), its pharmaceutically acceptable salts and/or prodrugs may be used in the prevention and/or treatment of autoimmune diseases, such as, for example, Multiple Sclerosis (MS), as well as in the prevention and/or treatment of transplant rejection....
5'-脱氧-5'-甲基硫代腺苷产品是5'-Deoxy-5'-methylthioadenosine (MTA) is an intermediate in the generation of adenine and methionine that is produced by the decarboxylation of S-adenosylmethionine. Acts as a potent agonist of adenosine receptors (Kis = 0.15, 1.13, 13.9, and 0.68 μM for A1...
5′-脱氧-5′-甲基硫腺苷(MTA)已被证明是蛋白质羧甲基转移酶的强抑制剂和多胺生物合成的天然副产物。据报道,这种核苷通过引起细胞凋亡强烈抑制某些细胞的生长。用该化合物处理细胞可抑制cAMP磷酸二酯酶,随后增加cAMP水平,导致细胞生长停止。更具体的研究表明,5′-脱氧-5′-甲基硫腺苷处理的细胞在细胞周期的M期显示...
MTA|Methylthioadenosine|NSC 335422|Vitamin L2; 5'-S-methyl-5'-thio-adenosine 供应商 Cayman Chemical 产品货号 15593-25 产品报价 ￥询价/25mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...
MTA, 5'-methylthioadenosineSIBA, 5'-isobutylthioadenosineAdoMet, S-adenosylmethioninePM II, S-adenosylmethionine:protein- O-carboxyl methyl transferaseFirst page of articledoi:10.1016/0014-5793(81)80250-5Patrizia GallettiAdriana OlivaCaterina Manna
The 2FA (2′-fluoroadenine) + MTA (5′-Methylthioadenosine) combination (100 mg/kg MTA; 20 mg/kg 2FA) inhibits tumor growth of four differentMTAP−human tumor cell lines in mouse xenograft models[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods....
体内:2FA(2'-氟腺嘌呤)+ MTA(5'-甲硫腺苷)组合(100 mg/kg MTA;20 mg/kg 2FA)抑制四种不同MTAP− 小鼠异种移植模型中的人肿瘤细胞系[3]. 参考文献: [1]. Tang Y, et al. 5'-Methylthioadenosine attenuates ischemia reperfusion injury after liver transplantation in rats. Inflammation. 2014;37(...
Although the biological occurrence of 5'-methylthioadenosine(MTA) and 5-methylthioribose (MTR) were recognized more than a halfcentury ago, very little light has been cast on the physiologic significanceof either substance. My studies were designed to extendour knowledge of the metabolism of MTA ...
5'-Methylthioadenosine/S-adenosylhomocysteine (MTA/AdoHcy) nucleosidase is a key enzyme in a number of critical biological processes in many microbes. This... Lee,E J. - 《Journal of Biological Chemistry》 被引量: 99发表: 2003年 Escherichia coli S-adenosylhomocysteine/5'-methylthioadenosine nucle...