Orf135 from is a new member of the Nudix (cleoside phosphate linked to some other moiety, ) hydrolase family of enzymes with substrate specificity for CTP, dCTP, and 5-methyl-dCTP. The gene has been cloned for overexpression, and the protein has been overproduced, purified, and ...
(1993). Direct induction of DNA hypermethylation insea urchin embryos by microinjection of 5-methyl dCTP stimulates early histone gene expression and leads to developmental arrest. Dev. Biol. 755, 75-86.Chen J, Maxson R, Jones PA. Direct induction of DNA hypermethy- lation in sea urchin ...