The phosphotransferase reaction product, FUMP, could be directly used for the successive synthesis of 5-fluorouridine diphosphate galactose using air-dried cells of Candida saitoana IFO 0768.doi:10.1016/0922-338X(94)90157-0Ken-Ichi Fujita
It might be independent of the well-known inhibition of the target enzymes, thymidylate synthetase and ribonucleoside diphosphate reductase, since there was no immediate apparent correlation in time between depletion of the pool sizes and the inhibition of the enzyme activities....