Drugs containing 5-ASA (aminosalicylates) are widely used in the management of inflammatory bowel disease (IBD) both for treating the active phases and maintaining remission. The use of these agents has been associated with the risk of developing a tubule-interstitial nephritis although the presence...
As SP seems to be responsible for most of the SASP side effects, new approaches for delivering only 5-ASA have emerged, either using pro-drugs (olsalazine, balsalazide) or oral mesalazine formulations "protecting" 5-ASA from release, absorption, and metabolism in the stomach and proximal ...
Evidence for treatment with 5-aminosalicylic acid (5-ASA) drugs is conflicting. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to examine this issue.METHODS:MEDLINE, EMBASE, and the Cochrane central register of controlled trials were searched (through ...
The Drug Program Information Network database is a population-based database that was established in 1995 and that records all prescription drugs. Results There were 25 cases of IBD identified as having CRC. These were matched with 348 cases of IBD who did not develop CRC. CRC cases were ...
Combinations of chemotherapeutic drugs ha... 被引量: 0发表: 2012年 Chemical constituents from the leaves of Michelia alba Emerging drug-resistance and drug-associated toxicities are two major factors limiting successful cancer therapy. Combinations of chemotherapeutic drugs ha... C.,Y.,Chen,... -...
OBJECTIVES:Evidence from randomized controlled trials (RCTs) for the use of 5-aminosalicylic acid (5-ASA) drugs in Crohn's disease (CD) in remission after a surgical resection is conflicting. We conducted a systematic review and meta-analysis of RCTs to examine this issue.METHODS:MEDLINE, ...
As such, clinicians should have knowledge of these drugs and patients' characteristics for proper prescription.doi:10.5124/jkma.2021.64.9.596You Sun KimJournal of the Korean Medical Association / Taehan Uisa Hyophoe Chi
There was no marked difference between the four 5-ASA drugs studied.Infants born of women who use 5-ASA drugs in early pregnancy have an increased risk of a congenital malformation, notably a cardiovascular defect. This could be a drug effect or an effect of an active inflammatory bowel ...
Evidence for treatment with 5-aminosalicylic acid (5-ASA) drugs is conflicting. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to examine this issue. METHODS: MEDLINE, EMBASE, and the Cochrane central register of controlled trials were searched (thro...
Conclusion 5-ASA-related renal disease was not found in our series, suggesting that the occurrence of renal impairment in IBD patients receiving these drugs is exceptional. Our results do not support the recommendation of serum creatinine monitoring in patients receiving 5-ASA treatment.Javier P. ...