PROBLEM TO BE SOLVED: To obtain a new DNA fragment, capable of coding a 5-aminolevulinic acid synthase having a specific amino acid sequence and useful for production, etc., of an enzyme capable of catalyzing a reaction for synthesizing 5- aminolevulinic acid having plant growth promoting ...
The E.coli host strain had an enormous effect on 5-aminolevulinic acid synthase activity and production of 5-aminolevulinic acid, with E.coli DH1 being best suited. RT-PCR of hemA mRNA indicated that the transcription of the hemA gene in the recombinant strain appeared to be higher than ...
Enhancer sequence of the 5-aminolevulinic acid synthase geneNucleic acid sequences mediating chemical compound induced 5-aminolevulinate synthase gene (ALAS1) expression are disclosed. Said sequences comprise at least a DR-4 binding site. Furthermore, in vitro methods for testing chemical compounds ...
(Shemin pathway), which Shemin and Russell first reported. It exists in animals, yeast, some protozoa, and purple non-sulfur photosynthetic bacteria. In this pathway, glycine and succinyl-CoA are condensed to 5-ALA under the catalysis of 5-aminolevulinic acid synthase (ALAS), with pyridoxal ...
What are the applications of 5-Aminolevulinic acid synthase 1 antibody? Sep 18 2022 Background[1-3] 5-Aminolevulinic acid synthase 1 antibody is a type of polyclonal antibody that can specifically bind to 5-Aminolevulinic acid synthase 1. It is mainly used in immunological experiment.. Why is...
5-Aminolevulinic acid synthase (ALAS-1) is the first rate controlling enzyme that controls cellular heme biosynthesis. Negative feedback regulation of ALAS-1 by the end product heme is well documented and provides the foundation for heme treatment of acute porphyrias, a group of diseases caused ...
The amino acid sequence of the cloned insert, derived from the nucleotide sequence (J.-M. Li, C. S. Russell, and S. D. Cosloy, J. Cell Biol. 107:617a, 1988), showed no homology with any ALA synthase sequenced to date. These results suggest that E. coli synthesizes ALA by the ...
5-Aminolevulinic acid ALAS: 5-Aminolevulinate synthase GSA: Glutamate-1-semialdehyde PBG: Porphobilinogen CPG: Coproporphyrinogen PPG: Protoporphyrinogen Kan: Kanamycin Amp: Ampicillin Chl: Chloramphenicol CRISPR: Clustered regularly interspaced short palindromic repeats sgRNA: Small-guide...
Lon Peptidase 1 (LONP1)-dependent Breakdown of Mitochondrial 5-Aminolevulinic Acid Synthase Protein by Heme in Human Liver Cells J,Schrum LW,Bonkovsky HL.Lonpeptidase 1 (LONP1)-dependent breakdown of mitochondrial5-aminolevulinic acid synthase protein by heme in human livercells. Jo... Q Tian,...
1.Study on Synthesis of 5-Aminolevulinic Acid Based on the Levulinic Acid乙酰丙酸合成5-氨基乙酰丙酸的研究 2.Cloning and Expression of 5-Aminolevulinic Acid Synthase Gene and Study on Biosynthesis of 5-Aminolevulinic Acid;5-氨基乙酰丙酸合成酶基因的克隆表达及生物合成5-氨基乙酰丙酸的研究 3.5-aminolevu...