5-Aminolevulinate dehydratase activity was studied in etiochloroplasts purified from radish cotyledons grown for 120 hr under continuous far-red light. The activity was mainly recovered from the stroma of the organelles, as previously observed, but also from the membrane fraction. The bound activity...
However, the endogenous toxin aminolevulinic acid (ALA) accumulates up to 100 fold in the mitochondrial matrix of patients with acute intermittent porphyria who lack cytosolic ALA dehydratase or have been exposed to lead, an inhibitor of the dehydratase. This also lowers heme levels for cytochrome/...
Production of 5-aminolevulinic acid by an Escherichia coli aminolevulinate dehydratase mutant that overproduces Rhodobacter sphaeroides aminolevulinate syn... Two Escherichia coli strains, a wild-type strain and a hemB mutant, which contained the hemA gene from Rhodobacter sphaeroides produced aminolevuli...
Article: Transgenic rescue of erythroid 5-aminolevulinate synthase-deficient mice results in the formation of ring sideroblasts and siderocytes
1. High level expression of His-tagged 5-aminolevulinate dehydratase from Bacillus subtilis; 含组氨酸标签的枯草杆菌5-氨基酮戊酸脱水酶的高效表达更多例句>> 2) δ-aminolevulinic acid dehydratase δ-氨基-γ-酮戊酸脱水酶 1. The genetic polymorphism of δ-aminolevulinic acid dehydratase (ALAD) in ...
Then the effects of precursors (glycine and succinate) and glucose, which is an inhibitor for ALA dehydratase as well as the carbon sources for cell growth, on the production of 5-aminolevulinate were investigated. Based on an optimal fed-batch culture system described in our previous work, ...
Background: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an ultrarare autosomal recessive disease, with only eight documented cases, all of whom were males. Although classified as an acute hepatic porphyria (AHP), induction of the rate limiting hepatic enzyme 5-aminolevulinic acid ...
Characterization of plastid 5-aminolevulinate dehydratase (ALAD;EC 4.2. 1.24) from spinach (Spinacia oleracea L.) by sequencing and compari- son with non-plant enzymes. Z. Naturforsch. 47c:77-84.Schaumburg, A, Schneider-Poetsch, HAW (1992) Characterization of plastid 5-aminolevulinate ...
Among the redox-dependent TBS enzymes, 5-aminolevulinic acid dehydratase (ALAD) was previously recognized to interact with reductants, such a thioredoxins or NADPH-dependent thioredoxin reductase C. In this report, we aim to verify the redox sensitivity of ALAD and identify th...
Berthe T, Klein-Eude D, Balangé AP (2003) Study of 5-aminolevulinate dehydratase in radish seedlings: are there housekeeping and light-induced enzymes? Plant Sci 164:395–405Berthe T, Klein-Eude D, Balange AP (2003) Study of 5-aminolevulinate dehydratase in radish seedlings: are there ...