The invention relates to a medicine composition composed of 0.1-100mg of one of statin lipid regulation medicines, 0.1-5mg of 5-methyltetrahydrofolic acid, and a pharmaceutically acceptable carrier. The invention also provides an application of the medicine composition in preparing medicines used for ...
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid. ...
Abstract of EP0388827This invention relates to the use of 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid and their pharmaceutically acceptable salts in the preparation
Abstract of EP0382019The present invention refers to the use of 5-methyltetrahydrofolic acid, of 5-formyltetrahydrofolic acid and of their pharmaceutically acceptable salts for th
The calcium salt of (6S)-5-methyltetrahydrofolic acid, calcium salt which belongs to the groupof folate vitamins (Vitamin B9, Folacin). It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. Cetirizine is a ...
mammalian enzyme both efficiently catalyze the conversion of dihydrofolic acid to tetrahydrofolic acid, the bacterial enzyme is sensitive to inhibition by trimethoprim by up to 40,000-fold lower concentrations than the mouse enzyme is. This difference explains the useful selective toxicity of ...
Whereas the bacterial enzyme and the mammalian enzyme both efficiently catalyze the conversion of dihydrofolic acid to tetrahydrofolic acid, the bacterial enzyme is sensitive to inhibition by trimethoprim by up to 40,000-fold lower concentrations than the mouse enzyme is. This difference explains the ...
methyltetrahydrofolic acid, and CoQ10, and neurotransmitters like dopamine and serotonin. Metabolite changes in pre-ASD newborns The top 4 most dysregulated metabolites in the pre-ASD newborns were sphingolipids (Fig.2e). Sphingosine-1-phosphate (S1P), ceramides and glycosphingolipids, like the ...
Tetrahydrofolic acid is an essential precursor in the de novo synthesis of the intermediate THYMIDINE monophoshpate (dTMP), precursor of DNA metabolite THYMIDINE triphosphate.?2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine (CAS NO.738-70-5) is also called as Trimethoprim ; Bactrim ; Bactrim...
[6R]-5,10-Methylenetetrahydrofolic acid is formulated as a lyophylised powder containing 100 mg per vial (calculated as free acid). Dosing: Rapid i.v. bolus injections at a fixed dose of 30, 60, 120 or 240 mg/m2, will be administered approximately 30 minutes after administration of 5-...