Azacitidine,5-Aza)、5-氮杂脱氧胞苷(地西他滨,5-Aza-2′-deoxycytidine,5-Aza-dc)、折布拉林(zebularine)、法扎拉滨(fazarabine)、氨基苯甲酸类(普鲁卡因、普鲁卡因胺)、茶多酚类(表没食子儿茶素没食子酯酸)、肼类(肼屈嗪)、邻苯二酰胺类(RG108)、反义寡核苷酸类(MG98)、三氧化二砷(Arsenic trioxide)等...
5-Aza-2'-deoxycytidine试剂CAS号:2353-33-5 纯度:≥98%化学式:C8H12N4O4熔点:分子量:228.21保存温度:Ambient产品介绍:acetic acid: water (1:1): 50 mg/mL2'-Deoxy-5-azacytidine, 4-Amino-1-(2-deoxy- -D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, DecitabineZhou JH, Yao YS, Wang LX, et ...
英文名称: 5-Aza-2′-deoxycytidine 总访问: 975 国产/进口: 进口 半年访问: 11 产地/品牌: SIGMA 产品类别: 生化试剂 规格: A0110-5MG 最后更新: 2013-1-5 货号: CAS 号: 参考报价: 350 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:微信新浪微博销售商: ...
[1]. Christman JK, et al. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene. 2002 Aug 12;21(35):5483-95. [2]. Li LH, et al. Cytotoxicity and mode of action of 5-azacytidine on L1210 le...
【目的】探讨5-Aza-2'-deoxycytidine(5-Aza-CdR)对肺癌 A549细胞 WWOX基因甲基化状态及其生物学行为的影响。【方法】将培养肺癌 A549细胞分为两组,一组加入5-Aza-CdR培养(观察组),一组未处理(对照组),采用甲基化特异性聚合酶连反应(MSP)检测两组 WWOX 基因甲基化状况;Western blot 法检测细胞WWOX蛋白的表达;...
5-Aza-2′-deoxycytidine 别名: 5-氮杂-2'-脱氧胞苷; 5-氮杂-2-脱氧胞苷; 5-氮杂-1-(2-脱氧-β-D-氟合亚硝脲)胞嘧啶; 地西他滨;;DECITABINE; 5-Aza-2'-deoxycytidine; Decitabine; 5-DEOXY-2'-AZACYTIDINE; 2'-deoxy-5-azacytidine; 5-azadeoxycytidine; 5-AZA-CDR; 4-Amino-1-(2 CAS号:...
英文名称5-Aza-2′-deoxycytidine 生化机理5′-Azadeoxycytidine causes DNA demethylation or hemi-demethylation. DNA demethylation can regulate gene expression by "opening" the chromatin structure detectable as increased nuclease sensitivity. This remodeling of chromatin structure allows transcription factors to ...
Biochem/physiol Actions5-Azacytidine is a deoxycytidine analog and a demethylating agent. It acts as a potential antineoplastic agent for acute myelogenous leukemia. 5-Azacytidine activates repressed genes by inhibiting DNA methylation. 5-Azacytidine also affects protein synthesis by altering the RNA fun...
[6] Qiu X, et al. Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes inthe transcriptome.PLoS One.2010 Sep 29;5(9). [7] Brueckner B,et al. Epigenetic reactivation of tumor suppressor genes...
英文名称:5-Aza-2'-deoxycytidine CAS:2353-33-5 包装信息:1kg 地西他滨专题 地西他滨能治什么病?有什么功效作用?地西他滨通常作为一种抗肿瘤药物,临床多用于骨髓增生异常综合征(MDS)、急性髓系白血病、慢性粒单核细胞白血病等恶性血液病的治疗。2024/8/22 9:28:22 ...