近日,南方科技大学李闯创团队在美国化学会《Accounts of Chemical Research》(《化学研究评述》)在线发表了题为“Total Synthesis of Natural Products with Bridged Bicyclo[m.n.1] Ring Systems via Type II [5+2] Cycloaddition”的特邀综述性文章。该综述性论文系统总结了李闯创团队近5年来,利用本课题组首次...
近期,美国威斯康星大学麦迪逊分校Weiping Tang教授与匹斯堡大学Peng Liu教授合作在oxidopyrylium ylide[5+2]环加成反应方面取得新进展。该工作以Intermolecular Regio- and Stereoselective Hetero-[5+2] Cycloaddition of Oxidopyrylium Ylides and Cyclic Imines为题在线发表于《德国应用化学》杂志(Angew. Chem. Int. Ed., ...
代表著作 1) Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009–2019) 2) 3) 4) 5) 6) Recent Publications 1)Total Synthesis of Natural Products with Bridged Ring Systems via Type II [5+2] Cycloaddition 2)Total Synthesis of Natural Products ...
The first metal-catalyzed intramolecular [5+2] cycloadditions of vinylcyclopropanes and alkenes: Scope, stereochemistry, and asymmetric catalysis The first studies of the metal-catalyzed [5+2] cycloadditions of vinylcyclopropanes and alkenes are described. These reactions proceed with exceptional diastereo...
(5-Ethynyl-2'-deoxyuridine(EdU) is a thymidine nucleoside analogues capable of insertion into DNA molecules being replicated during cell proliferation, and the subsequent [3 + 2] cycloaddition reaction of EdU with fluorescent azide catalyzed by copper can be developed as a method for detecting DNA...
www.nature.com/scientificreports OPEN Computational Prediction of One-Step Synthesis of Seven- membered Fused Rings by received: 27 October 2014 accepted: 23 June 2015 Published: 22 July 2015 (5+2) Cycloaddition Utilising Cycloalkenes Chen-Chen Zhou, Xiao-Na Ke & Xiu-Fang Xu The (5+...
这篇论文是他当年博士论文的重要延续和阐述,这也是标题“推敲”十五年的由来。 搞不清楚机理,那就一直坚持探索,余老师精益求精的精神,值得我们学习。 Mechanism and Stereochemistry of Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and Carbon Monoxide Revealed by Visual Kinetic ...
Notably, the challenging tricyclic 6-7-7 core of colchicine was efficiently introduced using an intramolecular oxidopyrylium-mediated [5+2] cycloaddition reaction.~2 This work represents the most efficient synthesis of colchicine reported to date with the highest enantioselectivity. 展开 关键词: ...
Mechanism and Stereochemistry of Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and Carbon Monoxide Revealed by Visual Kinetic Analysis and Quantum Chemical Calculations Yi Wang, Wei Liao, Yuanyuan Wang, Lei Jiao, and Zhi-Xiang Yu* ...
Ruthenium-catalyzed intramolecular [5 þ 2] cycloadditions. J. Am. Chem. Soc. 122, 2379–2380 (2000). 14. Trost, B. M. et al. Syntheses of seven-membered rings: ruthenium-catalyzed intramolecular [5 þ 2] cycloadditions. Chem. Eur. J. 11, 2577–2590 (2005). 15. Pellissier, ...