近日,南方科技大学李闯创团队在美国化学会《Accounts of Chemical Research》(《化学研究评述》)在线发表了题为“Total Synthesis of Natural Products with Bridged Bicyclo[m.n.1] Ring Systems via Type II [5+2] Cycloaddition”的特邀综述性文章。该综述性论文系统总结了李闯创团队近5年来,利用本课题组首次...
近期,美国威斯康星大学麦迪逊分校Weiping Tang教授与匹斯堡大学Peng Liu教授合作在oxidopyrylium ylide[5+2]环加成反应方面取得新进展。该工作以Intermolecular Regio- and Stereoselective Hetero-[5+2] Cycloaddition of Oxidopyrylium Ylides and Cyclic Imines为题在线发表于《德国应用化学》杂志(Angew. Chem. Int. Ed., ...
代表著作 1) Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009–2019) 2) 3) 4) 5) 6) Recent Publications 1)Total Synthesis of Natural Products with Bridged Ring Systems via Type II [5+2] Cycloaddition 2)Total Synthesis of Natural Products ...
总之,这种桥式-[5+2]反应是传统[5+2]反应研究中的一个突破性进展,为合成含有七元环的桥环化合物提供了一个新思路。 原文(扫描或长按二维码,识别后直达原文页面,或点此查看原文): Rh(I)-Catalyzed Bridged [5+2] Cycloaddition ofcis-Allene-vinylcyclopropanes to Synthesize Bicyclo[4.3.1]decane Skeleton An...
in the [5+2] cycloaddition reaction, focusing on metal-catalyzed [5+2] cycloadditions, [5+2] cycloadditions of metal-containing 5C components, [5+2] cycloadditions of oxidopyrylium and pyridinium species, [5+2] photocycloadditions, and domino reactions including a [5+2] cycloaddition. Two...
(5-Ethynyl-2'-deoxyuridine(EdU) is a thymidine nucleoside analogues capable of insertion into DNA molecules being replicated during cell proliferation, and the subsequent [3 + 2] cycloaddition reaction of EdU with fluorescent azide catalyzed by copper can be developed as a method for detecting DNA...
Ruthenium-Catalyzed Intramolecular [5 + 2] Cycloadditions. [J. Am. Chem. Soc. 2000 , 122 , 2379] The influence of substituents on which cyclopropyl bond cleaves in the cycloisomerization of cyclopropylenynes catalyzed by CpRu(N&tbd1;CCH(3))(3)(+)PF(6)(... BM Trost,FD Toste,H Shen ...
这篇论文是他当年博士论文的重要延续和阐述,这也是标题“推敲”十五年的由来。 搞不清楚机理,那就一直坚持探索,余老师精益求精的精神,值得我们学习。 Mechanism and Stereochemistry of Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and Carbon Monoxide Revealed by Visual Kinetic ...
The (5+2) cycloaddition reaction utilising cycloalkenes is rare, although it is one of the most efficient methods of constructing seven-membered fused rings because of its high atom- and step-economy. In this study, we used quantum mechanical calculations to predict the plausibility of using the...
Ruthenium-catalyzed intramolecular [5 þ 2] cycloadditions. J. Am. Chem. Soc. 122, 2379–2380 (2000). 14. Trost, B. M. et al. Syntheses of seven-membered rings: ruthenium-catalyzed intramolecular [5 þ 2] cycloadditions. Chem. Eur. J. 11, 2577–2590 (2005). 15. Pellissier, ...